Results 91 to 100 of about 155,102 (310)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
KiDS-Legacy: Constraining dark energy, neutrino mass, and curvature
Astronomy & AstrophysicsWe constrained minimally extended cosmological models with the cosmic shear analysis of the final data release from the Kilo-Degree Survey (KiDS-Legacy) in combination with external probes.
Reischke Robert +28 more
doaj +1 more source
The Data Handling System of the Helios Probes
, 1974 International Telemetering Conference Proceedings / October 15-17, 1974 / International Hotel, Los Angeles, CaliforniaThe Helios probes A and B will have a maximum distance of 2AU from Earth.
Pabst, Dietrich
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Nature CommunicationsProximity labeling with engineered ascorbate peroxidase (APEX) has been widely used to identify proteomes within various membrane-enclosed subcellular organelles. However, constructing protein distribution maps between two non-partitioned proximal spaces
Myeong-Gyun Kang +10 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
TITAN Probes Following CASSINI-HUYGENS
, 2008 This presentation was part of the session : Probe Missions to the Giant Planets, Titan and VenusSixth International Planetary Probe WorkshopThe NASA/ESA/ASI CASSINI-HUYGENS mission has renewed our view of the Saturnian system and its potential promises ...
Lebleu, Denis
core
Advancing Space Weather Research With the Next-Generation Space Weather Probes
Accurate characterization of ionospheric conditions is essential for improving space weather forecasting and mitigating its impacts on communication, navigation, and space-based systems.
Howes, Kade +5 more
core +1 more source
Comparison of quantitative real time PCR with Sequencing and ribosomal RNA-FISH for the identification of fungi in Formalin fixed, paraffin-embedded tissue specimens [PDF]
, 2011 Background: Identification of the causative agents of invasive fungal infections (IFI) is critical for guiding antifungal therapy. Cultures remain negative in a substantial number of IFI cases.
Rickerts Volker +17 more
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source