Results 111 to 120 of about 155,102 (310)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Calibration setup with metrological support for space qualified electric field probe

MATEC Web of Conferences, 2018
The article shows the results of calculations necessary for testing to approve the space qualified electric field probe used in outer space. A special electric field probe calibration setup was developed and manufactured, which allows testing a space ...
Kozlov Alexey, Shilov Alexander, Styuf Alexey, Doroshkin Alexander, Nikitenko Anatoly   +4 more
doaj   +1 more source

The Electric Field and Waves Instruments on the Radiation Belt Storm Probes Mission

, 2013
The Electric Fields and Waves (EFW) Instruments on the two Radiation Belt Storm Probe (RBSP) spacecraft (recently renamed the Van Allen Probes) are designed to measure three dimensional quasi-static and low frequency electric fields and waves associated ...
D. M. Malsapina, Mozer, F. S., Berg, P., Bolton, M. K., Baker, D. N., Donakowski, B.., K. Goetz, K. Harps, P. Berg, Harvey, P. R., Diaz-Aguado, M., V. Krasnoselskikh, Dizaz-Aguado, M., Hudson, M., S. Heavner, C. A. Cattell, P. R. Harvey, M. Hudson, J. Fischer, Ludlam, M., M. Diaz-Aguado, K. Kersten, Turin, P., Bolton, M.K, Smith, C., Krasnoselskikh, V., J. Albert, Donovan, E., Li, Xiaojian, M. K. Bolton, C. C. Chaston, R. Hochmann, I. Mann, Mann, I., Albert, J., Mozer, F.S., Foster, John C., R. E. Ergun, R. J. Strangeway, Bale, S. D., J. R. Wygant, G. Dalton, J. B. Tao, P. Turin, J. McCauley, Gordon, D., Harvey, P.R., J. C. Foster, Ergun, R., Bale, S.D., Donakowski, B., Rachelson, W., Cully, C. M., W. Rachelson, X. Li, C. M. Cully, F. S. Mozer, Foster, J.C., B. Donakowski, Brenneman, A., Tao, J.B., Wygant, J. R., Bonnell, J.W., Cattell, C. A., Kerstens, K., Heavner, S., Chaston, C.C., Bonnell, J. W., Baker, D.N, S. D. Bale, C. Smith, J. W. Bonnell, A. Brenneman, Malsapina, D.M, Goetz, K., Li, X., D. Gordon, D. N. Baker, Harps, K., Fischer, J., Strangeway, R. J., Dalton, G., E. Donovan, Shultz, C., Ergun, R. E., Malsapina, D. M., Hochmann, R., Wygant, J.R, M. Ludlam, C. Shultz, McCauley, J.   +90 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

The Van Allen Probes mission

, 2014
This collection of articles provides broad and detailed information about NASA’s Van Allen Probes (formerly known as the Radiation Belt Storm Probes) twin-spacecraft Earth-orbiting mission.
Burch, James, Fox, Nicola
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

THEMIS observations of ULF wave excitation in the nightside plasma sheet during sudden impulse events

, 2013
Sudden impulses (SIs) are an important source of ultra low frequency (ULF) wave activity throughout the Earth's magnetosphere. Most SI-induced ULF wave events have been reported in the dayside magnetosphere; it is not clear when and how SIs drive ...
Zong, Q.-G., Fu, S. Y., Shi, Q. Q., Zhou, X.Y., Zhou, X.Z., Zhou, X.-Y., Wang, Y. F., Pu, Z. Y., Tian, A. M., Ge, Y. S., Zhou, X.-Z., Angelopoulos, V., Kellerman, A., Hartinger, M., Zong, Q.G., Weygand, J., Yao, Z. H., Zhou, X. Y., Yao, Zhonghua, Zhou, X. Z., Zhang, H., Raeder, J., Zong, Q. G.   +22 more
core   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Telemetry Formats for the Space Station RF Links

, 1987
International Telemetering Conference Proceedings / October 26-29, 1987 / Town and Country Hotel, San Diego, CaliforniaThis paper discusses the formats that have been proposed for the manned Space Station space/ground RF link.
Marker, Walter
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