Results 51 to 60 of about 5,423,667 (297)

Early Hard X-Rays from the Nearby Core-collapse Supernova SN 2023ixf

The Astrophysical Journal Letters, 2023
We present NuSTAR observations of the nearby SN 2023ixf in M101 ( d = 6.9 Mpc) that provide the earliest hard X-ray detection of a nonrelativistic stellar explosion to date at δ t ≈ 4 days and δ t ≈ 11 days.
Brian W. Grefenstette, Murray Brightman, Hannah P. Earnshaw, Fiona A. Harrison, R. Margutti   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Simulated galactic cosmic ray exposure activates dose-dependent DNA repair response and down regulates glucosinolate pathways in arabidopsis seedlings

Frontiers in Plant Science, 2023
Outside the protection of Earth’s magnetic field, organisms are constantly exposed to space radiation consisting of energetic protons and other heavier charged particles.
Anirudha R. Dixit, Alexander D. Meyers, Brian Richardson, Jeffrey T. Richards, Stephanie E. Richards, Srujana Neelam, Howard G. Levine, Mark J. Cameron, Ye Zhang   +8 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

The Space Radiation Environment [PDF]

, 2008
The effects of the space radiation environment on spacecraft systems and instruments are significant design considerations for space missions. Astronaut exposure is a serious concern for manned missions.
Bourdarie, Sebastien, Xapsos, Michael A.
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

The effect of gamma irradiation on space charge behaviour and dielectric spectroscopy of low-density polyethylene [PDF]

, 2007
The influence of gamma irradiation on low-density polyethylene (LDPE) has been studied through space charge measurement and dielectric spectroscopy. Commercial LDPE film with a thickness of 100µm was irradiated with γ-rays at a dose rate of approximately
Chen Zou (1555771), Dissado, L. A., C. Zou, George Chen (179705), Fothergill, J., L. A. Dissado, Mingli Fu (6837953), Len A. Dissado (7583801), J. C. Fothergill, Chen, G., G. Chen, Fu, M., Fothergill, J. C., M. Fu, John C. Fothergill (7581362), Zou, C.   +15 more
core   +2 more sources

From Classical Radiation to Modern Radiation: Past, Present, and Future of Radiation Mutation Breeding

Frontiers in Public Health, 2021
Radiation mutation breeding has been used for nearly 100 years and has successfully improved crops by increasing genetic variation. Global food production is facing a series of challenges, such as rapid population growth, environmental pollution and ...
Liqiu Ma, Liqiu Ma, Fuquan Kong, Fuquan Kong, Kai Sun, Ting Wang, Tao Guo   +6 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source