Results 61 to 70 of about 4,278,960 (299)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
An analytical solution to the problem of determining the parameters of motion of an orbiter’s center of mass is presented on the basis on the results of measurements carried out using the optical system of a space robot located in orbit coplanar to that ...
V. M. Ananenko +2 more
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
A Proposal for a Multi-Drive Heterogeneous Modular Pipe- Inspection Micro-Robot [PDF]
This paper presents the architecture used to develop a micro-robot for narrow pipes inspection. Both the electromechanical design and the control scheme will be described. In pipe environments it is very useful to have a method to retrieve information of
Brunete González, Alberto +3 more
core +1 more source
Evaluation of the tether based locomotion using image processing in the REX-J mission
Image processing is one of the methods used to measure position/attitude for robot control and there are hopes that it can be applied to space robot missions, including REX-J (Robot EXperiment on ISS/JEM).
Satoshi SUZUKI +9 more
doaj +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Space Detumbling Robot Arm Deployment Path Planning Based on Bi-FMT* Algorithm
In order to avoid damage to service satellites and targets during space missions and improve safety and reliability, it is necessary to study how to eliminate or reduce the rotation of targets.
Ning Chen, Yasheng Zhang, Wenhua Cheng
doaj +1 more source
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Vibration Suppression Control of a Space Robot with Flexible Appendages Based on Simple Dynamic Model [PDF]
This paper discusses a vibration suppression control method for a space robot with a rigid manipulator and flexible appendage. A suitable dynamic model that considers the coupling between the manipulator and flexible appendage was developed for the ...
Yoshida, K. +5 more
core
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source

