Results 131 to 140 of about 5,668,523 (337)
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source
The Needle is Moving in CA K-8 Science: Integration with ELA, Integration of the Sciences, and Returning Science as a K-8 Core Subject [PDF]
, 2016 This first EII evaluation publication discusses one of the major shifts above, namely the shift to integrated instruction. The integration of science and ELA is the focus of one section, and the integration of the science disciplines (i.e., earth/space ...
Ashley Iveland +4 more
core
Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
UVSat: a concept of an ultraviolet/optical photometric satellite
, 2017 Time-series photometry from space in the ultraviolet can be presently done with only a few platforms, none of which is able to provide wide-field long-term high-cadence photometry.
Baran, A. +27 more
core
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Molecular Oncology, EarlyView.Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza +5 more
wiley +1 more source
Editorial: Applications of statistical methods and machine learning in the space sciences
Frontiers in Astronomy and Space Sciences, 2023 Bala Poduval +4 more
doaj +1 more source
Unorthodoxies and controversies in planetary and space science [PDF]
Unorthodoxies and controversies in planetary and space ...
Strughold, H.
core +1 more source
Molecular Oncology, EarlyView.Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban +12 more
wiley +1 more source