Results 171 to 180 of about 13,924,091 (398)
HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4
FEBS Open Bio, EarlyView.Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang +11 more
wiley +1 more source
How congress deals with science and technology [PDF]
, 1964 Congress deals with space science and ...
Daddario, E. Q.
core +1 more source
Coupled fixed point theorems in partially ordered ε-chainable metric spaces [PDF]
arXiv, 2010 In this paper, we introduce the notion of partially ordered {\epsilon}-chainable metric spaces and we derive new coupled fixed point theorems for uniformly locally contractive mappings on such spaces.
arxiv
American Geophysical Union Program on the Impact of Space Research on the Sciences [PDF]
, 1960 openalex +1 more source
Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations
FEBS Open Bio, EarlyView.We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley +1 more source
Generalized normed spaces and Fixed point Theorems [PDF]
Journal of mathematics and computer science 13 (2014) 157-167, 2018 G\"ahler ([4],[5]) introduced and investigated the notion of 2-metric spaces and 2-normed spaces in sixties. These concepts are inspired by the notion of area in two dimensional Euclidean space. In this paper, we choose a fundamentally different approach and introduce a possible generalization of usual norm retaining the distance analogue properties ...
arxiv