Results 121 to 130 of about 63,291,506 (350)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Space use in Syrmia during the Migration and Avar periods
Communicationes Archaeologicae HungariaeLying between the Danube and Sava rivers, the region of Syrmia used to be the northern fringe of the Roman Empire and, later on, the southernmost land of the Avars.
Ivan Bugarski
doaj +1 more source
Exploring redshift-space distortions in large-scale structure
, 2018 We explore and compare different ways large-scale structure observables in redshift-space and real space can be connected. These include direct computation in Lagrangian space, moment expansions and two formulations of the streaming model.
Vlah, Zvonimir, White, Martin
core +1 more source
Space Use and Movement of a Neotropical Top Predator: The Endangered Jaguar
PLoS ONE, 2016 Accurately estimating home range and understanding movement behavior can provide important information on ecological processes. Advances in data collection and analysis have improved our ability to estimate home range and movement parameters, both of ...
R. Morato +29 more
semanticscholar +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Gas density detector for use in space [PDF]
Gas density detector for meteoroid ...
Meshejian, W. K. +3 more
core +1 more source
Better spaced seeds using Quadratic Residues
Journal of Computer and System Sciences, 2013 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Lavinia Egidi, Giovanni Manzini
openaire +3 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Egyptian Journal of Remote Sensing and Space Sciences, 2016 To reduce the human influence on natural resources and to identify an appropriate land use, it is essential to carry out scientific land evaluations. Such kind of analysis allows identifying the main limiting factors for the agricultural production and ...
Mohamed A.E. AbdelRahman +2 more
doaj +1 more source