Results 141 to 150 of about 63,291,506 (350)
Journal of Zoological and Botanical GardensNonbreeding white rhino bulls are traditionally housed individually in zoos, but space limitations require the exploration of alternative techniques. There are no studies of group-housed bulls, and the feasibility of managing a bachelor group is unknown.
Lara C. Metrione +3 more
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Avian Conservation and EcologyKnowledge of space use provides insight into a species’ habitat requirements needed for conservation. Little is known about space use of the near threatened Kirtland’s Warbler ( Setophaga kirtlandii ) wintering in The Bahamas, and how the warbler’s home ...
Joseph M Wunderle, Jr. +5 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Space ecosynthesis: An approach to the design of closed ecosystems for use in space [PDF]
The use of closed ecological systems for the regeneration of wastes, air, and water is discussed. It is concluded that such systems, if they are to be used for the support of humans in space, will require extensive mechanical and physico-chemical support.
Averner, M. M., Macelroy, R. D.
core +1 more source
Quantum phase space trajectories with application to quantum cosmology
, 2018 We develop an approach to quantum dynamics based on quantum phase space trajectories. The latter are built from a unitary irreducible representation of the symmetry group of the respective classical phase space.
Bergeron, Hervé +2 more
core +1 more source
Scaling up movements: from individual space use to population patterns
, 2016 Studying multiple individuals from multiple populations would add knowledge about the proportion of different movement strategies (migratory vs. resident) and how space use patterns vary within and across populations.
Andrew M. Allen +5 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Silicon solar cells for space use: Present performance and trends [PDF]
A technology assessment of present performance levels and current fabrication methods and designs is ...
Ho, F. F., Iles, P. A., Khemthong, S.
core +1 more source