Results 71 to 80 of about 8,495,084 (302)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Symplectic Geometry of Supersymmetry and Nonlinear Sigma Model
, 1993 Recently it has been argued, that Poincar\'{e} supersymmetric field theories admit an underlying loop space hamiltonian (symplectic) structure. Here shall establish this at the level of a general $N=1$ supermultiplet.
Atiyah +8 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Woodland caribou calving fidelity: Spatial location, habitat, or both?
Ecology and EvolutionIndividuals that isolate themselves to give birth can use more than one strategy in choosing birth sites to maximize reproductive success. Previous research has focused on the consistency in the use of the same birth‐site across years (i.e., spatial ...
P. D. Walker +4 more
doaj +1 more source
The use of acoustics in space exploration
, 2007 In recent years increased attention has been paid to the potential uses of acoustics forextraterrestrial exploration. The extent to which acoustics per se is used in these studiesvaries greatly. First, there are the cases in which acoustics is simply the
Leighton, T.G.
core
Chemical tagging can work: Identification of stellar phase-space structures purely by chemical-abundance similarity [PDF]
, 2016 Chemical tagging promises to use detailed abundance measurements to identify spatially separated stars that were in fact born together (in the same molecular cloud), long ago.
Casey, Andrew R. +12 more
core +3 more sources
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Ecology and EvolutionTo conserve wide‐ranging species in degraded landscapes, it is essential to understand how the behavior of animals changes in relation to the degree and composition of modification.
Nathan R. Hahn +9 more
doaj +1 more source
The peculiar breeding biology of the Amazonian frog Allobates subfolionidificans (Aromobatidae)
Anais da Academia Brasileira de CiênciasAllobates subfolionidificans is a vulnerable and endemic leaf-litter frog from the state of Acre, Brazilian Amazonia. We monitored a population of A.
JESUS R.D. SOUZA +2 more
doaj +1 more source