Results 81 to 90 of about 8,495,084 (302)

Asymptotically Schroedinger Space-Times: TsT Transformations and Thermodynamics

, 2010
We study the complete class of 5-dimensional asymptotically Schroedinger space-times that can be obtained as the TsT transform of a 5-dimensional asymptotically AdS space-time. Based on this we identify a conformal class of Schroedinger boundaries.
Hartong, Jelle, Rollier, Blaise
core   +1 more source

Regenerative Urban Space: A Box for Public Space Use [PDF]

, 2019
The essay addresses the issues of centrality and reactivation of urban public spaces, illustrating the project ‘multiplyCITY: container TOOLS.’ The project is composed of a system of ‘devices’ that can be placed in urban or natural contexts and is capable of hosting multiple functions for citizens, even in total energy autonomy.
E. Ginelli, G. Pozzi, G. Lazzati, D. Pirillo, G. Vignati   +4 more
openaire   +3 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Temporal variations in female moose responses to roads and logging in the absence of wolves

Ecology and Evolution
Animal movements, needed to acquire food resources, avoid predation risk, and find breeding partners, are influenced by annual and circadian cycles. Decisions related to movement reflect a quest to maximize benefits while limiting costs, especially in ...
Mireille Gagnon, Frédéric Lesmerises, Martin‐Hugues St‐Laurent   +2 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The space use by Przewalski's horses of the semi-free population during first years after their reintroduction to Orenburg State Nature Reserve, Russia

Nature Conservation Research: Заповедная наука, 2019
In 2015, the Joint Directorate of State Nature Reserves «Orenburg» and «Shaitan-Tau» (FSFI «Orenburg Reserves») launched the Programme on establishing a semi-free population of the Przewalski's horse Equus ferus przewalskii in the 165 km2 Pre-Urals ...
Daniel Klich, Tatjana L. Zharkikh, Rafał Łopucki, Rafilia T. Bakirova, Evgeniy A. Bulgakov, Vladimir Yu. Petrov   +5 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Space Colonization Using Space-Elevators from Phobos [PDF]

AIP Conference Proceedings, 2003
A novel approach is examined for creating an industrial civilization beyond Earth. The approach would take advantage of the unique configuration of Mars and its moon Phobos to make a transportation system capable of raising mass from the surface of Mars to space at a low cost.
openaire   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Reimagining soil stewardship in the anthropocene: Nature-Positive pathways, pedological perspectives, and land use innovations for soil health and security

Soil Security
Soils underpin terrestrial ecosystems and human well-being, yet they remain highly vulnerable to degradation driven by climate change, unsustainable land use, and intensifying anthropogenic pressures.
Mohamed A.E. AbdelRahman
doaj   +1 more source