Results 71 to 80 of about 40,337 (302)
BMC Genomics, 2020 Background Candida albicans is an opportunistic pathogenic yeast, which could become pathogenic in various stressful environmental factors including the spaceflight environment.
Jiaping Wang +7 more
doaj +1 more source
The effect of long-term spaceflight on drug potency and the risk of medication failure
npj Microgravity, 2023 Pharmaceuticals selected for exploration space missions must remain stable and effective throughout mission timeframes. Although there have been six spaceflight drug stability studies, there has not been a comprehensive analytical analysis of these data.
J. F. Reichard +4 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post +4 more
wiley +1 more source
Longitudinal MRI-visible perivascular space (PVS) changes with long-duration spaceflight
Scientific Reports, 2022 Humans are exposed to extreme environmental stressors during spaceflight and return with alterations in brain structure and shifts in intracranial fluids.
Kathleen E. Hupfeld +15 more
doaj +1 more source
Dermatologic manifestations in spaceflight: a review [PDF]
Dermatology Online Journal, 2018 With manned missions to Mars on the horizon, understanding and preparing for the medical conditions these astronauts might face becomes vital. According to the literature, the most commonly reported medical events in space are dermatological in nature. Dermatologic conditions rarely threaten an astronaut's life or the mission.
Dunn, Carly, Boyd, McKenna, Orengo, Ida
openaire +4 more sources
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims Therapeutic drug monitoring for astronauts faces limitations in conventional blood sampling and sample management onboard the international space station. Here, we explore the feasibility of dried blood spot (DBS) collection during parabolic flights (PF) to overcome these constraints.
Audrey Derobertmasure +8 more
wiley +1 more source
Effects and Solutions on the Human Body After Long-Duration Space Flights [PDF]
, 2019 During the Cold War, President John F. Kennedy made it a mission for the National Aeronautics and Space Administration (NASA) to accomplish a lunar landing and return to Earth.
Esquivel Patricio, Jose Jaime
core +1 more source
Bone strength and composition in spacefaring rodents: systematic review and meta-analysis
npj Microgravity, 2022 Studying the effects of space travel on bone of experimental animals provides unique advantages, including the ability to perform post-mortem analysis and mechanical testing.
Matthew Goldsmith +4 more
doaj +1 more source
Brain structural plasticity with spaceflight [PDF]
npj Microgravity, 2016 AbstractHumans undergo extensive sensorimotor adaptation during spaceflight due to altered vestibular inputs and body unloading. No studies have yet evaluated the effects of spaceflight on human brain structure despite the fact that recently reported optic nerve structural changes are hypothesized to occur due to increased intracranial pressure ...
Ajitkumar P. Mulavara +3 more
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Journal of Sleep Research, EarlyView.ABSTRACT For the first time, we examined bidirectional predictors between baseline night (B2) and recovery night 1 (R1) actigraphic sleep measures and neurobehavioural indices during total sleep deprivation (TSD) in a 5‐day experiment with 32 healthy adults. During the B2 and R1 nights, wrist actigraphy assessed sleep indices. Neurobehavioural measures
Lauren N. Pasetes, Namni Goel
wiley +1 more source