Results 71 to 80 of about 6,642 (220)
Experimental Physiology, EarlyView.Abstract Microgravity is associated with stature increases, back pain and post‐flight intervertebral disc (IVD) herniation. This study aims to determine whether 30 s seated 50% body weight (BW) axial loading is comparable to 15 min sitting upright in 1 g upon changes in stature, anterior lumbar IVD height (via ultrasound), passive vertebral stiffness ...
David Marcos‐Lorenzo +6 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Astronauts experience combined exposure to a cephalad fluid shift and mild hypercapnia during space missions, potentially contributing to health problems. Such combined exposure may weaken dynamic cerebral autoregulation. The magnitude of cephalad fluid shift varies between individuals, and dynamic cerebral autoregulation may be affected more ...
Tomokazu Kato +2 more
wiley +1 more source
npj MicrogravityStaphylococcus aureus colonizes the nares of approximately 30% of humans, a risk factor for opportunistic infections. To gain insight into S. aureus virulence potential in the spaceflight environment, we analyzed RNA-Seq, cellular proteomics, and ...
Matthew R. Hauserman +3 more
doaj +1 more source
An experimentally informed computational model of neurovestibular adaptation to altered gravity
Experimental Physiology, EarlyView.Abstract Transitions to altered gravity environments result in acute sensorimotor impairment for astronauts, leading to serious mission and safety risks in the crucial first moments in a new setting. Our understanding of the time course and severity of impairment in the early stages of adaptation remains limited and confounded by unmonitored head ...
Victoria G. Kravets, Torin K. Clark
wiley +1 more source
Experimental Physiology, EarlyView.Abstract A reduction in cerebral blood flow (CBF) has been observed during spaceflight and bed rest. We aimed to examine the magnitude and regional heterogeneity of the decrease in CBF during bed rest compared to posture changes on Earth. Seventeen participants (age, 29 ± 9 years, 7 females) were studied in the upright and supine posture and over 3 ...
Carmen Possnig +8 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Blood flow restriction (BFR) has been identified as a potential countermeasure to mitigate physiological deconditioning during spaceflight. Guidelines recommend that tourniquet pressure be prescribed relative to limb occlusion pressure (LOP); however, it is unclear whether body tilting or reduced gravity analogues influence LOP.
Patrick Swain, Nick Caplan, Luke Hughes
wiley +1 more source
Jumping on the moon as a potential exercise countermeasure
Experimental Physiology, EarlyView.Abstract The Moon's gravitational field strength (17% Earth's gravity) may facilitate the use of bodyweight jumping as an exercise countermeasure against musculoskeletal and cardiovascular deconditioning in reduced gravity settings. The present study characterised the acute physiological and kinetic responses to bodyweight jumping in simulated Lunar ...
Patrick Swain +4 more
wiley +1 more source
Hypogravity simulation using the Variable Gravity Suspension System: A technical report
Experimental Physiology, EarlyView.Abstract Human movement has evolved within Earth's gravitational environment (1 g; −9.81 m s−2). Future human exploration of terrestrial bodies, including the Moon (0.17 g; −1.62 m s−2) and Mars (0.38 g; −3.71 m s−2), will require astronauts to live and work within reduced gravitational environments (hypogravity).
Patrick Swain +7 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Manned space exploration to distant destinations, including Mars, continues to be an aspiration of humankind. Space travel does, however, present many challenges to the body, amongst which adaptation to microgravity is perhaps the largest. For instance, both short and long manned spaceflight missions have shown substantial deleterious effects ...
Gerard McMahon +2 more
wiley +1 more source