The highly rearranged mitochondrial genomes of the crabs Maja crispata and Maja squinado (Majidae) and gene order evolution in Brachyura [PDF]
, 2017 We sequenced the mitochondrial genomes of the spider crabs Maja crispata and Maja squinado (Majidae, Brachyura). Both genomes contain the whole set of 37 genes characteristic of Bilaterian genomes, encoded on both \u3b1- and \u3b2-strands.
AD Miller +67 more
core +1 more source
Cooperativity dominates the genomic organization of p53-response elements: a mechanistic view.
PLoS Computational Biology, 2009 p53-response elements (p53-REs) are organized as two repeats of a palindromic DNA segment spaced by 0 to 20 base pairs (bp). Several experiments indicate that in the vast majority of the human p53-REs there are no spacers between the two repeats; those ...
Yongping Pan, Ruth Nussinov
doaj +1 more source
Structural basis of copper-efflux-regulator-dependent transcription activation
iScience, 2021 Summary: The copper efflux regulator (CueR), a representative member of mercury resistance regulator (MerR) family metalloregulators, controls expression of copper homeostasis-regulating genes in bacteria.
Wei Shi +8 more
doaj +1 more source
Functional analysis of transcribed spacers of yeast ribosomal DNA. [PDF]
The EMBO Journal, 1990 Making use of an rDNA unit, containing oligonucleotide tags in both the 17S and 26S rRNA gene, we have analyzed the effect of various deletions in the External Transcribed Spacer (ETS) and in one of the Internal Transcribed Spacers 1 (ITS1) on the process of ribosome formation in yeast.
W, Musters +4 more
openaire +2 more sources
Improved split fluorescent proteins for endogenous protein labeling. [PDF]
, 2017 Self-complementing split fluorescent proteins (FPs) have been widely used for protein labeling, visualization of subcellular protein localization, and detection of cell-cell contact.
Feng, Siyu +5 more
core +2 more sources
An ancestral genomic sequence that serves as a nucleation site for de novo gene birth.
PLoS ONE, 2022 The process of gene birth is of major interest with current excitement concerning de novo gene formation. We report a new and different mechanism of de novo gene birth based on the finding and the characteristics of a short non-coding sequence situated ...
Nicholas Delihas
doaj +2 more sources
CRISPR interference directs strand specific spacer acquisition.
PLoS ONE, 2012 BackgroundCRISPR/Cas is a widespread adaptive immune system in prokaryotes. This system integrates short stretches of DNA derived from invading nucleic acids into genomic CRISPR loci, which function as memory of previously encountered invaders.
Daan C Swarts +3 more
doaj +1 more source
RAG-1 Mutations Associated with B-Cell-Negative SCID Dissociate the Nicking and Transesterification Steps of V(D)J Recombination [PDF]
, 2001 Some patients with B-cell-negative severe combined immune deficiency (SCID) carry mutations in RAG-1 or RAG-2 that impair V(D)J recombination. Two recessive RAG-1 mutations responsible for B-cell-negative SCID, R621H and E719K, impair V(D)J recombination
Chang, Fu-Chung +2 more
core +2 more sources
Evaluation of five regions as DNA barcodes for identification of Lepista species (Tricholomataceae, Basidiomycota) from China [PDF]
PeerJ, 2019 Background Distinguishing among species in the genus Lepista is difficult because of their similar morphologies. Methods To identify a suitable DNA barcode for identification of Lepista species, we assessed the following five regions: internal ...
Siyu Wang +5 more
doaj +2 more sources
The structure of the maize ribosomal DNA spacer region
Nucleic Acids Research, 1986 A combination of a single stranded plasmid vector and ordered deletions were used to determine the complete nucleotide sequence of a rDNA spacer region isolated from the DNA of maize Black Mexican Sweet suspension cells. The sequence reveals the presence of ten "200 base" subrepeats within the maize rDNA spacer region.
M D, McMullen +3 more
openaire +3 more sources