Results 61 to 70 of about 170,575 (305)

Transcription of spacer sequences flanking the rat 45S ribosomal DNA gene. [PDF]

Molecular and Cellular Biology, 1987
The transcriptional activity of spacer sequences flanking the rat 45S ribosomal DNA (rDNA) gene were studied. Nascent RNA labeled in in vitro nuclear run-on reactions hybridized with both 5' and 3' spacer regions. The highest level of hybridization was seen with an rDNA fragment containing tandem repeats of a 130-base-pair sequence upstream of the 45S ...
C A, Harrington, D M, Chikaraishi
openaire   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

psbA-trnH Intergenic Spacer profile of Wax Apple (Syzygium samarangense (Blume) Merr. & L.M. Perry) Cultivars

Jurnal Ilmu Pertanian Indonesia
The fruit known as wax apple, scientifically named Syzygium samarangense (Blume) Merr. & L.M. Perry, is a well-liked agricultural product originating from Demak Regency in the Central Java Province.
Tiara Dwi Meilina, Syifara Chika, Muhammad Rifqi Hariri, Asri Febriana, Arnia Sari Mukaromah   +4 more
doaj   +1 more source

A functional analysis of the spacer of V(D)J recombination signal sequences. [PDF]

PLoS Biology, 2003
During lymphocyte development, V(D)J recombination assembles antigen receptor genes from component V, D, and J gene segments. These gene segments are flanked by a recombination signal sequence (RSS), which serves as the binding site for the recombination
Alfred Ian Lee, Sebastian D Fugmann, Lindsay G Cowell, Leon M Ptaszek, Garnett Kelsoe, David G Schatz   +5 more
doaj   +1 more source

I-motif-stapled and spacer-dependent multiple DNA nanostructures

RSC Advances, 2016
The DNA spacers between duplexes and i-motif structures are critical for the morphology of assembled pH-responsive DNA nanostructures, which is very instructive for fabrication of distinct-scale molecular devices in the future.
Jiangtao Ren, Tianshu Wang, Erkang Wang, Jin Wang   +3 more
openaire   +1 more source

Differentiation between Aspergillus flavus and Aspergillus parasiticus from Pure Culture and Aflatoxin-Contaminated Grapes Using PCR-RFLP Analysis of aflR-aflJ Intergenic Spacer [PDF]

, 2011
Aflatoxins (AFs) represent the most important single mycotoxin-related food safety problem in developed and developing countries as they have adverse effects on human and animal health. They are produced mainly by Aspergillus flavus and A.
Atoui, Ali, El Khoury, André, Kallassy, Mireille, Lebrihi, Ahmed, Lteif, Roger, Rizk, Toufic   +5 more
core   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Reprogramming the endogenous type I CRISPR‐Cas system for simultaneous gene regulation and editing in Haloarcula hispanica

mLife, 2022
The type I system is the most widely distributed CRISPR‐Cas system identified so far. Recently, we have revealed the natural reprogramming of the type I CRISPR effector for gene regulation with a crRNA‐resembling RNA in halophilic archaea.
Kaixin Du, Luyao Gong, Ming Li, Haiying Yu, Hua Xiang   +4 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Amplified Ribosomal DNA from Xenopus laevis Has Heterogeneous Spacer Lengths [PDF]

Proceedings of the National Academy of Sciences, 1974
Eco R 1 restriction endonuclease makes two cuts in each repeating unit of amplified ribosomal DNA (rDNA) from Xenopus laevis . The locations of these cuts have been established by comparison of the secondary structure of single-stranded Eco R 1
P K, Wellauer, R H, Reeder, D, Carroll, D D, Brown, A, Deutch, T, Higashinakagawa, I B, Dawid   +6 more
openaire   +2 more sources