Results 41 to 50 of about 1,562,506 (284)

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

The Sums and Products of Commuting AC-Operators

open access: yesInternational Journal of Industrial Engineering and Production Research, 2007
: In this paper, we exhibit new conditions for the sum of two commuting AC-operators to be again an AC-operator. In particular, this is satisfied on Hilbert space when one of them is a scalar-type spectral operator.
M.B Ghaemi, p. Spain
doaj  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Post-Truth Politics in Action? Representation of the Media in Spanish Radical Parties’ Electoral Campaigns

open access: yesMedia and Communication
Recent research on the EU institutional response to post-truth politics has shown a gradual shift of focus from external threats to internal democratic challenges, including populist parties and elections.
Taru Haapala, Juan Roch
doaj   +1 more source

The Flexible Institutionalization Process of Puma Currency in Seville, Spain

open access: yesPartecipazione e Conflitto, 2020
Grassroots groups depend on dynamic and fluid interactions with high trust to retain their identity. At the same time, a stable structure and division of labour with rules and hierarchies is necessary to sustain their organisation and social influence ...
Georgina M. Gómez   +1 more
doaj   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Review of “Hispanic-Turkish relations (1402-2017) Some considerations” by Ricardo Evaristo Santos

open access: yesTürkiyat Mecmuası
Evaristo Santos, Ricardo, Las relaciones hispanoturcas (1402-2017) Algunas consideraciones, Madrid: Turpin Editores, 2017, ISBN: 978-84-96911-2-6.
Berksan Gülsoy
doaj   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

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