Results 41 to 50 of about 3,698,416 (278)

Is Catching Up Possible in Europe? [PDF]

open access: yesRomanian Journal of European Affairs, 2002
In the current debate on the European Union enlargement there is an apparent mythical belief that, if the set of preconditions set by Brussels are fulfilled, rapid and sustained economic growth would ensue, which would allow the newly admitted countries ...
Daniel Dăianu
doaj  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Desarrollo de efectos cerámicos como acabados superficiales, mediante tecnología de inyección digital

open access: yesBoletín de la Sociedad Española de Cerámica y Vidrio, 2012
Ferro Spain SA has tackled the practical viability of tile surfaces decoration by means of applying layers of reduced thickness by means of the use of digital injection technology by inkjet and, specifically, relating to effects and superficial finishes ...
Spain S.A., Ferro
doaj  

Spain and Portugal’s Efforts to Grant Citizenship to the Sephardic Jews in Turkey

open access: yesYakın Dönem Türkiye Araştırmaları, 2021
A majority of the Jews living in Turkey are descendants of Sephardic Jews expelled from Spain and Portugal during the end of the fifteenth century.
Reyhan Gülşen
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Spain [PDF]

open access: yes, 2005
Details of the definitive version are available at http://www.ashgate.com/default.aspx?page=637&calcTitle=1&title_id=6415&edition_id ...
Morales, Laura   +2 more
core   +2 more sources

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

Neuroimaging features of immune-related adverse events due to immune checkpoint inhibitor therapy

open access: yesInsights into Imaging
Immune checkpoint inhibitors, a type of intravenous immunotherapy targeting T cells, are being increasingly used in cancer treatment. They work by increasing the immune system’s response to tumour cells, through blockade of inhibitory “checkpoint ...
Arian Lasocki, Lavinia Spain
doaj   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz   +3 more
wiley   +1 more source

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