Results 21 to 30 of about 143 (122)

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, Volume 13, Issue 37, 3 July 2026.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

Honey as a Xylindein-Stimulatory Media for Chlorociboria Species

Colorants
Fungi in the Chlorociboria genus produce a blue pigment called xylindein—a pigment with high UV stability, photovoltaic capacity, and which is used as a historic wood colorant.
Olivia Queisser, Hayden Houck, Padraic Duggan, Bo MacGill, Seri C. Robinson   +4 more
doaj   +1 more source

Analytical Derivations of the Neighborhood Effect Averaging Problem (NEAP) and Its Two Variants: From Representative Samples to Unbiased Health Effect Sizes and Critical Insights Into Health Geography

Geographical Analysis, Volume 58, Issue 3, July 2026.
ABSTRACT Accurate environmental exposure measurements that maximally mitigate contextual errors are necessary for reliable modeling of human health outcomes. Recent advances in environmental exposure measurements highlight a new manifestation of contextual errors called the neighborhood effect averaging problem (NEAP).
Yang Liu, Mei‐Po Kwan
wiley   +1 more source

Structural Role and Mechanical Impact of Zirconia in Lithium Disilicate Glass

Journal of the American Ceramic Society, Volume 109, Issue 6, June 2026.
The effect of ZrO2 addition on the structure, topology, and mechanical properties of lithium disilicate glass is investigated using topological constraint theory (TCT), molecular dynamics simulations, and experiments. Zirconia acts as a network former, increasing packing density, rigidity, hardness, and elastic modulus.
Bahareh Kheilnezhad, Hongyeun Kim, Kiera Palmer, Scott Kroeker, Seong H. Kim, John C. Mauro, Maziar Montazerian   +6 more
wiley   +1 more source

The Development Potential of Spalted Wood Artifacts in China—An Analysis

Colorants
Spalted wood is a natural material characterized by distinctive colors and patterns from wood decay fungi as they digest their substrate and leave behind colored secretions.
Chen Li, Seri C. Robinson
doaj   +1 more source

Microglia Mitochondria Support Neuronal Maturation via Metabolic and Transcriptional Reprogramming in Human 3D In Vitro Brain Model

Advanced Science, Volume 13, Issue 25, 4 May 2026.
xx xx. ABSTRACT Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by disrupted neuronal circuit maturation. Emerging evidence implicates microglial function and mitochondrial regulation as contributors to ASD‐associated biology, yet the mechanisms linking these processes to neuronal development remain poorly defined ...
Sydney P. Sterben, Charitha C. Anamala, Sahan B. S. Kansakar, Vaishnavi Koduri, Volha Liaudanskaya   +4 more
wiley   +1 more source

Function of the spalt/spalt-related gene complex in positioning the veins in the Drosophila wing

Mechanisms of Development, 2000
Spalt and Spalt-related encode conserved Zn-finger proteins that mediate the function of the TGF-beta molecule Decapentaplegic during the positioning of veins in the Drosophila wing. Here we show that Spalt and Spalt-related regulate the vein-specific expression of the transcription factors of the knirps and iroquois gene complexes, delimiting their ...
de Celis, Jose F., Barrio, Rosa
openaire   +2 more sources

Drosophila spalt/spalt-related mutants exhibit Townes-Brocks' syndrome phenotypes [PDF]

Proceedings of the National Academy of Sciences, 2003
Mutations in SALL1 , the human homolog of the Drosophila spalt gene, result in Townes-Brocks' syndrome, which is characterized by hand/foot, anogenital, renal, and ear anomalies, including sensorineural deafness. spalt
P D Si, Dong, Sokol V, Todi, Daniel F, Eberl, Grace, Boekhoff-Falk   +3 more
openaire   +2 more sources

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

MedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi, Shahin Ramazi, Mona Darvazi, Sepideh Yoosefi, Melika Abbasi, Shirin Farsad   +5 more
wiley   +1 more source

The Benefits of Access: Evidence from Private Meetings with Portfolio Firms

The Journal of Finance, Volume 81, Issue 2, Page 739-789, April 2026.
ABSTRACT We use large language models to analyze the content of 4,700 private meetings between a large active asset manager and its portfolio firms. The high‐level meetings convey mostly soft information about the firm, and little about industry or market. Fund manager meetings focus on business models and financial metrics, while governance specialist
MARCO BECHT, JULIAN FRANKS, HANNES F. WAGNER   +2 more
wiley   +1 more source