Results 31 to 40 of about 334 (137)

The Development Potential of Spalted Wood Artifacts in China—An Analysis

open access: yesColorants
Spalted wood is a natural material characterized by distinctive colors and patterns from wood decay fungi as they digest their substrate and leave behind colored secretions.
Chen Li, Seri C. Robinson
doaj   +1 more source

Function of the spalt/spalt-related gene complex in positioning the veins in the Drosophila wing

open access: yesMechanisms of Development, 2000
Spalt and Spalt-related encode conserved Zn-finger proteins that mediate the function of the TGF-beta molecule Decapentaplegic during the positioning of veins in the Drosophila wing. Here we show that Spalt and Spalt-related regulate the vein-specific expression of the transcription factors of the knirps and iroquois gene complexes, delimiting their ...
de Celis, Jose F., Barrio, Rosa
openaire   +2 more sources

Drosophila spalt/spalt-related mutants exhibit Townes-Brocks' syndrome phenotypes [PDF]

open access: yesProceedings of the National Academy of Sciences, 2003
Mutations in SALL1 , the human homolog of the Drosophila spalt gene, result in Townes-Brocks' syndrome, which is characterized by hand/foot, anogenital, renal, and ear anomalies, including sensorineural deafness. spalt
P D Si, Dong   +3 more
openaire   +2 more sources

Structural Role and Mechanical Impact of Zirconia in Lithium Disilicate Glass

open access: yesJournal of the American Ceramic Society, Volume 109, Issue 6, June 2026.
The effect of ZrO2 addition on the structure, topology, and mechanical properties of lithium disilicate glass is investigated using topological constraint theory (TCT), molecular dynamics simulations, and experiments. Zirconia acts as a network former, increasing packing density, rigidity, hardness, and elastic modulus.
Bahareh Kheilnezhad   +6 more
wiley   +1 more source

Microglia Mitochondria Support Neuronal Maturation via Metabolic and Transcriptional Reprogramming in Human 3D In Vitro Brain Model

open access: yesAdvanced Science, Volume 13, Issue 25, 4 May 2026.
xx xx. ABSTRACT Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by disrupted neuronal circuit maturation. Emerging evidence implicates microglial function and mitochondrial regulation as contributors to ASD‐associated biology, yet the mechanisms linking these processes to neuronal development remain poorly defined ...
Sydney P. Sterben   +4 more
wiley   +1 more source

Development of an industrial process for spalted wood in high value furniture applications

open access: yes, 2018
Demand for natural wood material with aesthetic character is on the increase, with the furniture industry turning its focus to spalted wood, a term given to any coloration in wood in response to a fungus.
Morris, Hugh; id_orcid
core   +5 more sources

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi   +5 more
wiley   +1 more source

The Benefits of Access: Evidence from Private Meetings with Portfolio Firms

open access: yesThe Journal of Finance, Volume 81, Issue 2, Page 739-789, April 2026.
ABSTRACT We use large language models to analyze the content of 4,700 private meetings between a large active asset manager and its portfolio firms. The high‐level meetings convey mostly soft information about the firm, and little about industry or market. Fund manager meetings focus on business models and financial metrics, while governance specialist
MARCO BECHT   +2 more
wiley   +1 more source

Molecular Glue Degraders Redefining Targeted Therapies From Discovery to Therapeutic Applications

open access: yesMedComm – Oncology, Volume 5, Issue 1, March 2026.
Molecular glue degraders (MGDs) constitute an emerging class of therapeutic agents poised to revolutionize the paradigm of targeted drug discovery. By reprogramming E3 ubiquitin ligases to degrade proteins of interest (POI) via a transient formation of a ternary complex mediated by protein–protein interactions, MGDs surpass the intrinsic limitations of
Jinfeng Wen   +3 more
wiley   +1 more source

4‐(5‐Chloro‐3‐(3,4,5‐trimethoxybenzoyl)‐1H‐indol‐1‐yl)benzenesulfonamide: A Novel Polypharmacology Agent to Target Carbonic Anhydrase IX and XII With Improved Selectivity, Wnt/β‐Catenin Signaling Pathway, and P‐Glycoprotein

open access: yesChemMedChem, Volume 21, Issue 4, 25 February 2026.
Polypharmacology is expected to produce higher therapeutic efficacy and lower cytotoxic and side effects. Compound 15 exhibited strong inhibition of the human carbonic anhydrase isoforms IX and XII and selectivity toward the adverse isoforms I and II.
Michela Puxeddu   +21 more
wiley   +1 more source

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