Results 31 to 40 of about 142 (122)

A Clinical Guidance for the Management of Patients With Hepatoid Adenocarcinoma and A Case Series

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Hepatoid adenocarcinoma (HAC) is a rare extrahepatic tumor of non‐germ cell origin that morphologically resembles hepatocellular carcinoma (HCC). HAC has a propensity to metastasize to the liver and therefore may be mistaken for HCC. There is a lack of standardized treatment protocols, and further studies are needed to evaluate the benefit of ...
Christina Liava, Sudhakar Venkatesh, Michael S. Torbenson, Patrick S. Kamath, Moira Hilscher   +4 more
wiley   +1 more source

Single‐Cell RNAseq Identifies Heterogeneity in Myoblasts From Older Adults With Differences Related to Muscle Mass and Function

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Ageing is associated with the loss of muscle mass and function, with consequences for metabolic health, frailty and independence in later life. The aim of this study was to investigate the transcriptional heterogeneity of human proliferating muscle satellite/stem cells (myoblasts) from older adults and how this heterogeneity may ...
Mark A. Burton, Emma S. Garratt, Hanan Y. Sharkh, Matthew O. Hewitt, Elie Antoun, Leo D. Westbury, Elaine M. Dennison, Nicholas C. Harvey, Cyrus Cooper, Harnish P. Patel, Keith M. Godfrey, Karen A. Lillycrop   +11 more
wiley   +1 more source

Tumor Microenvironments in Malignant Ovarian Germ Cell Tumors: MHC Class I Loss and T‐Cell Exhaustion in Dysgerminoma

Cancer Science, Volume 117, Issue 2, Page 566-575, February 2026.
Malignant ovarian germ cell tumor subtypes exhibit distinct tumor microenvironments. Dysgerminomas harbor abundant nonexhausted T cells, with progenitor exhausted T cells present in 60% of PD‐1–positive cases. However, MHC class I expression is lost across all analyzed subtypes, suggesting that restoring class I expression in dysgerminomas may enhance ...
Miya Nakashima, Takeshi Iwasaki, Yoshihiro Katayama, Masatoshi Shimo, Ken Takigawa, Naomi Shimada, Michiko Matsushita, Satoshi Kuwamoto, Shinya Sato, Masato Toya, Kohta Miyawaki, Koichi Akashi, Kiyoko Kato, Yoshinao Oda   +13 more
wiley   +1 more source

Subtle Discrimination

The Journal of Finance, Volume 81, Issue 1, Page 329-369, February 2026.
ABSTRACT We introduce the concept of subtle discrimination—biased acts that cannot be objectively ascertained as discriminatory. When candidates compete for promotions by investing in skills, firms' subtle biases induce discriminated candidates to overinvest when promotions are low‐stakes (to distinguish themselves from favored candidates) but ...
ELENA S. PIKULINA, DANIEL FERREIRA
wiley   +1 more source

Lisa Spalt

, 2022
Lisa Spalt (* 1970), österr ...
Straub, Wolfgang, Dürr, Claudia, Raunig, Elisabeth   +2 more
openaire   +1 more source

Evolution of Plasticity in Response to Ethanol Between Recently Separated Populations of D. melanogaster With Different Ecological Histories

Ecology and Evolution, Volume 16, Issue 1, January 2026.
We identified: (1) differences in gene expression among each locale; (2) changes in gene expression in response to treatment; (3) genotype‐specific changes in gene expression in response to treatment. ABSTRACT While there is abundant theoretical work on the evolution of phenotype plasticity, empirical support has lagged.
George Boateng‐Sarfo, Franz Scherping, Murad Mammadov, Sarah Signor   +3 more
wiley   +1 more source

Gene Expression Analysis Provides Insights Into the Functional and Developmental Differentiations of Pleopodal Lungs in a Terrestrial Isopod Crustacean, Porcellio scaber

Evolution &Development, Volume 27, Issue 4, December 2025.
Transcriptomic analysis of pleopods in Porcellio scaber reveals gene expression linked to pleopodal lung development, identifying candidate regulatory genes and highlighting developmental changes as drivers of lung development in terrestrial isopod crustaceans.
Naoto Inui, Akifumi Yao, Sumio Udagawa, Kohei Oguchi, Yoshinobu Hayashi, Toru Miura   +5 more
wiley   +1 more source

A Case of Synchronous Bilateral Spermatocytic Tumor

IJU Case Reports, Volume 8, Issue 6, Page 553-557, November 2025.
ABSTRACT Introduction Spermatocytic tumor is rare, accounting for approximately 1% of all testicular neoplasms. It is clinically and pathologically distinct from classical seminoma and typically presents as a unilateral, slow‐growing mass in older men. Case Presentation A 54‐year‐old man presented with painless bilateral scrotal swelling.
Mao Saito, Hiromichi Katayama, Satoko Sato, Sota Oguro, Takuro Goto, Yohei Satake, Takuma Sato, Yoshihide Kawasaki, Naoki Kawamorita, Akihiro Ito   +9 more
wiley   +1 more source

Imatinib decreases germ cell survival and germline stem cell proliferation in rodent testis ex vivo and in vitro

Andrology, Volume 13, Issue 6, Page 1575-1591, September 2025.
Abstract Background Imatinib and dasatinib are tyrosine kinase inhibitors (TKIs) increasingly used to treat several diseases in both children and adults at fertile age. We have previously shown that imatinib has adverse effects on developing testis, and imatinib‐treated male patients have been reported to have reduced sperm counts.
Anna Eggert, Sini Laasanen, Mirja Nurmio, Aida Wahlgren, Kirsi Jahnukainen, Kim Eerola, Miisael Nieminen, Opeyemi Olotu, Noora Kotaja, Juho‐Antti Mäkelä, Jorma Toppari   +10 more
wiley   +1 more source

Regulation of Drosophila spalt gene expression

Mechanisms of Development, 1997
The region-specific homeotic gene spalt is involved in the specification of terminal versus trunk structures during early Drosophila embryogenesis. Later in development spalt activity participates in specific processes during organogenesis and larval imaginal disc development.
Kuehnlein, R., Broenner, G., Taubert, H., Schuh, R.   +3 more
openaire   +3 more sources