Results 91 to 100 of about 962,783 (305)
, 2005 We discuss a simple sparse linear problem that is hard to learn with any algorithm that uses a linear combination of the training instances as its weight vector. The hardness holds even if we allow the learner to embed the instances into any higher dimensional feature space (and use a kernel function to define the dot product between the embedded ...
Warmuth, Manfred, Vishwanathan, S
openaire +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Transit : a story inspired by Melbourne's taxi entrepreneurs from Hadchit, North Lebanon
, 2006 Cover title: Tansa. Exhibition held at Span Galleries from 14-18 November 2006. "TOW is a research and arts practice and undertakes projects centred on the Lebanese migration to Australia"--Cover verso.Bibliography: p ...
Span Galleries
core
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
, 2006 1431-1436AlCl3-catalyzed diazocoupling of 1-aryl/heteroaryl-3-methyl-1H-pyrazol-2-in-5-ones 1 in water with different aryl/heteroaryldiazonium salts affords the corresponding hetcroarylazopyrazoloncs 2 as colored products with high yields.
Hassan, Mohamed A +2 more
core
Span-Based Information Extraction and Beyond
Span-based information extraction (SIE) is a set of natural language processing and information extraction tasks which aim to extract the span of interest from digital text and assign corresponding span classes that describe the nature of that text.
Yifan Ding (21022829)
core +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source