Results 71 to 80 of about 962,783 (305)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Psychosocial therapy model to reduce anxiety levels in hemodialysis patients
MedisainsBackground: Chronic kidney disease (CKD) is a global health issue that significantly impacts the quality of life of patients undergoing hemodialysis. Anxiety is one of the common psychological challenges faced by these patients.
Fajar Ariyanto +2 more
doaj +1 more source
Сахарный диабет, 2018 Background: Diabetic retinopathy (DR) is one of the most common causes of blindness in patients with diabetes mellitus (DM) that is why it’s necessary to study the epidemiological characteristics of this complication. Aims: The aim of the study was
Dmitry V. Lipatov +8 more
doaj +1 more source
, 2006 1504-1510A facile synthesis of some novel 5-alkyl-1,2-dihydro-spiro[4H-3, 1-benzoxazine-2,3'[3H]indol]-4,2'-diones, in high yields, has been carried out classically as well as under microwave irradiation in solvent free conditions. Microwave irradiation
Saxena, Anjali +4 more
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Synthesis of chemiluminescent biotinyl naphtho[1,8-de][1,2]diazepine-1,4-diones
, 2006 2512-2522A new chemiluminescent seven membered cyclic peri hydrazide, 6-amino-2,3-dihydronaphtho[1,8-de][1,2]diazepine- 1,4-dione (AH, 4), and five of its biotin conjugates with various spacer groups are synthesized.
Reddy, A Ram, Murthy, N V Krishna
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Cloud-SPAN Prenomics: Overview
, 2022 Cloud-SPAN is a collaboration between the Department of Biology, University of York and The Software Sustainability Institute funded by the UKRI innovation scholars award (Project Reference: MR/V038680/1) which trains researchers, and the research ...
Emma Rand +5 more
core +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Patterns of desire : Greer Honeywill
, 2006 Catalogue of an exhibition held at Span Galleries, Melbourne, Victoria, 4 - 29 April 2006.Includes bibliographical ...
Span Galleries
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