Results 61 to 70 of about 962,783 (305)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
quam ... pro doctoralibus in utroque iure honoribus & privilegiis solenniter consequendis, censurae publicae submittet Sigismundus Span, Hauensteinio-Bohem. consiliarius Rutheno-Gräzensis ad diem ... ianuar.
Span, Sigismund
core +1 more source
Test on 15m Span Composite Cellular Beam
, 2014 NoCellular beams are the preferred form of long span construction in multi-storey buildings. For efficient design of composite cellular beams, asymmetric sections are often manufactured in which the bottom flange is larger than the top flange.
Aggelopoulos, E.S. +2 more
core +4 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Factors influence the severity of premenopause syndrome
MedisainsBackground: Premenopause syndrome triggers more severe physical and psychological problems and the emergence of various diseases. The limited research on the factors causing the severity of Premenopause syndrome has resulted in a lack of efforts to ...
Megawati Sinambela +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Autism and Menstrual Health: A Scoping Review of Challenges and Interventions
Journal of Clinical & Developmental PsychologyAutism spectrum conditions have historically been studied primarily in males, due to social biases and the tendency of females to mask core traits, leaving women’s specific experiences underexplored.
Maria Clara Cavallini +2 more
doaj +1 more source
Relações entre TRABALHO, EDUCAÇÃO e SOCIEDADE: Uma proposta de intervenção pedagógica
, 2019 Convidamos vocês para conhecer uma proposta de intervenção pedagógica, idealizada como instrumento orientativo para o desenvolvimento de um curso de curta duração, direcionado à formação inicial ou
Nunes, Albino de Oliveira +2 more
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