Results 51 to 60 of about 962,783 (305)
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
COMPETÊNCIAS DOS BIBLIOTECÁRIOS NA GESTÃO DOS DADOS DE PESQUISA
No cenário científico, e-Science é o ambiente de profusão dos dados científicos, que demandam práticas de gestão, que, por sua vez, implicam no surgimento de competências para sua implementação.
Maria Helena Ferreira Xavier da Silva Silva +4 more
doaj
Apperception and Object —Comments on Mario Caimi’s Reading of the B-Deduction
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Dennis Schulting
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Reseña del libro editado en 2018 por Dieter Hüning y Stefan Klingner titulado ...jenen süβen Traum träumen. Kants Friedensschrift zwischen objektiver Geltung und Utopie (Baden Baden / Nomos) que compila artículos dedicados a la filosofía jurídica y su ...
Miguel Ángel Ramírez Cordón
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source

