Results 51 to 60 of about 962,783 (305)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Normas de edición

open access: yesRevista de Estudios Kantianos, 2022
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Equipo editorial .
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

COMPETÊNCIAS DOS BIBLIOTECÁRIOS NA GESTÃO DOS DADOS DE PESQUISA

open access: yesCiência da Informação, 2020
No cenário científico, e-Science é o ambiente de profusão dos dados científicos, que demandam práticas de gestão, que, por sua vez, implicam no surgimento de competências para sua implementação.
Maria Helena Ferreira Xavier da Silva Silva   +4 more
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Dieter Hüning y Stefan Klingner (eds.): ...jenen süßen Traum träumen. Kants Friedensschrift zwischen objektiver Geltung und Utopie. Baden Baden, Nomos, 2018

open access: yesRevista de Estudios Kantianos, 2020
Reseña del libro editado en 2018 por Dieter Hüning y Stefan Klingner titulado ...jenen süβen Traum träumen. Kants Friedensschrift zwischen objektiver Geltung und Utopie (Baden Baden / Nomos) que compila artículos dedicados a la filosofía jurídica y su ...
Miguel Ángel Ramírez Cordón
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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