Results 51 to 60 of about 215,708 (267)

Study on the sag of ultra high voltage conductor with large-tonnage tension insulator string

open access: yesEnergy Reports, 2022
The aim of this paper is to establish a unified state equation of overhead line mechanics. An accurate calculation method of non-uniform load sag is proposed based on the simply supported beam theory. It is suitable for isolated span and continuous span.
Ruiyong Zhang   +3 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Effects of pontic span and fiber reinforcement on fracture strength of multi-unit provisional fixed partial dentures

open access: yesJournal of Dental Sciences, 2019
Background/purpose: Clinically, PMMA resin is extensively used for fabricating provisional FPDs. However, fracture often occurs due to the unsatisfactory mechanical strength, especially within connectors of long-span provisional FPDs. The purpose of this
Min-Chieh Chang   +5 more
doaj   +1 more source

Simple Length-Constrained Minimum Spanning Trees

open access: yes
Added Ravi ...
Hershkowitz, D Ellis, Huang, Richard Z
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

RELATIONSHIP BETWEEN SIZE AND THE RATE OF CALCIUM–DEPENDENT PROTEOLYSIS IN SKELETAL MUSCLES IN THE ATLANTIC SALMON (SALMO SALAR L.) AND BROWN TROUT (SALMO TRUTTA L.) FROM RIVERS DRAINING TO THE WHITE SEA (ARKHANGELSK REGION)

open access: yesTransactions of the Karelian Research Centre of the Russian Academy of Sciences, 2018
The activity level of calcium-dependent proteases of the calpain family in skeletal muscles of the atlantic salmon (Salmo salar L.) and brown trout (Salmo trutta L.) from some watercourses (the Zolotitsa River and Lopatka stream) draining to the White ...
Nadezhda Kantserova   +4 more
doaj   +1 more source

Planar Length-Constrained Minimum Spanning Trees

open access: yes
In length-constrained minimum spanning tree (MST) we are given an $n$-node graph $G = (V,E)$ with edge weights $w : E \to \mathbb{Z}_{\geq 0}$ and edge lengths $l: E \to \mathbb{Z}_{\geq 0}$ along with a root node $r \in V$ and a length-constraint $h \in \mathbb{Z}_{\geq 0}$.
Hershkowitz, D Ellis, Huang, Richard Z
openaire   +2 more sources

On the total length of the random minimal directed spanning tree [PDF]

open access: yesAdvances in Applied Probability, 2006
In Bhatt and Roy's minimal directed spanning tree construction for a random, partially ordered set of points in the unit square, all edges must respect the ‘coordinatewise’ partial order and there must be a directed path from each vertex to a minimal element. We study the asymptotic behaviour of the total length of this graph with power-weighted edges.
Penrose, M.D., Wade, Andrew
openaire   +4 more sources

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Home - About - Disclaimer - Privacy