Surface heterogeneity impacts on boundary layer dynamics via energy balance partitioning [PDF]
The role of land-atmosphere interactions under heterogeneous surface conditions is investigated in order to identify mechanisms responsible for altering surface heat and moisture fluxes.
D. B. Mechem +2 more
core +2 more sources
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Spatial nonlocal pair correlations in a repulsive 1D Bose gas [PDF]
We analytically calculate the spatial nonlocal pair correlation function for an interacting uniform 1D Bose gas at finite temperature and propose an experimental method to measure nonlocal correlations.
A. G. Sykes +10 more
core +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Design curves for optimizing stability of herringbone-grooved journal bearings [PDF]
Curves span wide range of operating conditions, including: lubricant compressibility numbers from 0 to 80, bearing length-to-diameter ratios from 1/4 to 2, and either rotating or stationary grooved ...
Fleming, D. P., Hamrock, B. J.
core +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Don't break a leg: Running birds from quail to ostrich prioritise leg safety and economy in uneven terrain [PDF]
Cursorial ground birds are paragons of bipedal running that span a 500-fold mass range from quail to ostrich. Here we investigate the task-level control priorities of cursorial birds by analysing how they negotiate single-step obstacles that create a ...
Birn-Jeffery, A V +6 more
core +7 more sources
Networks of Recurrent Events, a Theory of Records, and an Application to Finding Causal Signatures in Seismicity [PDF]
We propose a method to search for signs of causal structure in spatiotemporal data making minimal a priori assumptions about the underlying dynamics. To this end, we generalize the elementary concept of recurrence for a point process in time to recurrent
B. B. Mandelbrot +14 more
core +2 more sources
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Fatigue Life Prediction of Submarine Pipelines with Varying Span Length and Position
Free spans of submarine pipelines are prone to be subjected to vortex-induced vibration (VIV) under the action of currents, leading to fatigue damage of submarine pipelines.
Daoyu Jiang +4 more
doaj +1 more source

