Results 41 to 50 of about 226,339 (260)

Membrane-Spanning Molecular Lengths as an Agnostic Biosignature

Astrobiology
We explore a hypothesis in which the detection of classes of lipid-like molecules with similar abundance-averaged lengths would constitute a biosignature for other worlds. This is based on the functional requirements of membrane molecules: they must have enough hydrophobic length to not diffuse away from the membrane, be capped by one or two ...
Michael J. Malaska, Hilda Sandström, Amy E. Hofmann, Robert Hodyss, Linnea Rensmo, Mark van der Meulen, Martin Rahm, Morgan L. Cable, Jonathan I. Lunine   +8 more
openaire   +2 more sources

Noisy signals: Does rating volatility depend on the length of the consumption span?

Economic Modelling, 2023
This paper investigates the informational content of online reviews. For the case of hotels, we model how the length of the stay shapes the variance of review scores. Grounded on violations of temporal monotonicity, errors in recall and hedonic adaptation theories, we first present a characterization of how the consumption span affects the non ...
David Boto-García, Veronica Leoni
openaire   +4 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Fatigue Life Prediction of Submarine Pipelines with Varying Span Length and Position

Journal of Marine Science and Engineering
Free spans of submarine pipelines are prone to be subjected to vortex-induced vibration (VIV) under the action of currents, leading to fatigue damage of submarine pipelines.
Daoyu Jiang, Xiaowei Huang, Deping Zhao, Haijing Yang, Guoqiang Tang   +4 more
doaj   +1 more source

Prevalence of Two-Syllable Digits Affecting Forward Digit Span Test Score

SAGE Open, 2016
The word length effect shows a connection between word length and working memory performance. Although the relationship between digit verbal length and digit span has been investigated between languages, it has not been investigated within a language. It
Lars E. Egner, Stefan Sütterlin, Ricardo G. Lugo   +2 more
doaj   +1 more source

Traffic Load Models for Latvian Road Bridges With Span Length up to 30 Meters

The Baltic Journal of Road and Bridge Engineering, 2014
Bridges are structures that propose the service life up to hundred years. However, the actual traffic load models significantly differ from the characteristic load models used in the design. The analysis of former design codes of bridges used in the last
Andris Paeglitis, Ainars Paeglitis
doaj   +1 more source

Planar Length-Constrained Minimum Spanning Trees

Proceedings of the 58th Annual ACM Symposium on Theory of Computing
In length-constrained minimum spanning tree (MST) we are given an $n$-node graph $G = (V,E)$ with edge weights $w : E \to \mathbb{Z}_{\geq 0}$ and edge lengths $l: E \to \mathbb{Z}_{\geq 0}$ along with a root node $r \in V$ and a length-constraint $h \in \mathbb{Z}_{\geq 0}$.
D Ellis Hershkowitz, Richard Z Huang
openaire   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source