Results 51 to 60 of about 233,765 (215)

Colour and Morphometric Variation of Donacid Bivalves from Nepa Beach, Madura Island, Indonesia

Biosaintifika: Journal of Biology & Biology Education, 2017
Donacid bivalves vary in colour, pattern, and the shape of the shells. A population of donacid bivalves had been found in the northern shore of Madura Island, Indonesia.
Reni Ambarwati, Ulfi Faizah
doaj   +1 more source

Study on the sag of ultra high voltage conductor with large-tonnage tension insulator string

Energy Reports, 2022
The aim of this paper is to establish a unified state equation of overhead line mechanics. An accurate calculation method of non-uniform load sag is proposed based on the simply supported beam theory. It is suitable for isolated span and continuous span.
Ruiyong Zhang, Jinke Li, Xinyu Zhao, Cheng Yao   +3 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

A multi-season investigation of glacier surface roughness lengths through in situ and remote observation [PDF]

The Cryosphere, 2019
The roughness length values for momentum, temperature, and water vapour are key inputs to the bulk aerodynamic method for estimating turbulent heat flux.
N. Fitzpatrick, V. Radić, B. Menounos
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Effects of pontic span and fiber reinforcement on fracture strength of multi-unit provisional fixed partial dentures

Journal of Dental Sciences, 2019
Background/purpose: Clinically, PMMA resin is extensively used for fabricating provisional FPDs. However, fracture often occurs due to the unsatisfactory mechanical strength, especially within connectors of long-span provisional FPDs. The purpose of this
Min-Chieh Chang, Chun-Cheng Hung, Wen-Cheng Chen, Shang-Chun Tseng, Yung-Chung Chen, Jen-Chyan Wang   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

RELATIONSHIP BETWEEN SIZE AND THE RATE OF CALCIUM–DEPENDENT PROTEOLYSIS IN SKELETAL MUSCLES IN THE ATLANTIC SALMON (SALMO SALAR L.) AND BROWN TROUT (SALMO TRUTTA L.) FROM RIVERS DRAINING TO THE WHITE SEA (ARKHANGELSK REGION)

Transactions of the Karelian Research Centre of the Russian Academy of Sciences, 2018
The activity level of calcium-dependent proteases of the calpain family in skeletal muscles of the atlantic salmon (Salmo salar L.) and brown trout (Salmo trutta L.) from some watercourses (the Zolotitsa River and Lopatka stream) draining to the White ...
Nadezhda Kantserova, Liudmila Lysenko, Denis Efremov, Aleksey Veselov, Nina Nemova   +4 more
doaj   +1 more source