Results 31 to 40 of about 135,087 (312)
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
BiD: Textos Universitaris de Biblioteconomia i Documentació, 2014 Objectius: analitzar la situació de la gestió de projectes com a matèria en els estudis universitaris de grau i postgrau (màster) d'Informació i Documentació a Iberoamèrica (l'Argentina, Bolívia, el Brasil, Colòmbia, Costa Rica, Cuba, l'Equador, el ...
Cobo Serrano, Silvia +1 more
doaj +1 more source
Early swelling response to phytohemagglutinin is lower in older toads [PDF]
PeerJ, 2018 The effects of age on performance of life-history traits are diverse, but a common outcome is senescence, an irreversible deterioration of physical and physiological capabilities of older individuals.
Francisco Javier Zamora-Camacho +1 more
doaj +2 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Transfer, 2017 Bearing in mind the important role of literary mediators –translators, critics, editors, etc,- in building up the world literary space, this study intends to do research on the image of the Spanish America that was discursively built by those mediators ...
Denise Mallmann Vallerius
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
JPhys MaterialsThe surface chemistry and inter-connectivity within perovskite nanocrystals play a critical role in determining the electronic interactions. They manifest in the Coulomb screening of electron–hole correlations and the carrier relaxation dynamics, among ...
Esteban Rojas-Gatjens +7 more
doaj +1 more source
Historia de las primeras traducciones al español de Madame Bovary (1875-1935) [PDF]
Çédille: Revista de Estudios Franceses, 2019 This article documents the history of the first Spanish translations of Madame Bovary in Spain and Latin America over more than half a century: from 1875, when the first version was published in Spanish, until the Spanish Civil War, turning point in the ...
María José Hernández Guerrero
doaj
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source