Results 41 to 50 of about 13,497,395 (308)
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Revista Tradumàtica, 2019 Hasta el momento, la investigación sobre la interpretación asistida y mediada por tecnología ha adoptado un enfoque centrado principalmente en la interpretación como producto para entender el papel de la tecnología durante esta actividad.
Christopher D. Mellinger
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Spanish Relief Committee's correspondence concerning refugees of the Spanish civil war
, 1939 Correspondence with Australian Commonwealth Government, Australian League of Nations Union, NSW Council for the Relief of Spanish Distress, United Associations of Women, YMCA, Joyce Metcalf and others, together with copies of minutes of Executive ...
Spanish Relief Committee
core +1 more source
Shoreline response to sea-level rise according to equilibrium beach profiles
Scientific Reports, 2023 Shoreline position is a key parameter of a beach state, often used as a descriptor of the response of the system to changes in external forcing, such as sea-level rise.
Pau Luque +5 more
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Scientific ReportsBiogenic CaCO3 microparticles obtained from oyster shells Crassostrea gigas were used as starting material for synthesizing Co2+, Mg2+ and Mn2+-doped apatite nano-submicroparticles, through a one-step hydrothermal conversion. The conversion was completed
Sandra María Cano-Plá +11 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Understanding Spanish Jihadist Terrorism
This book offers the first systematic account in English of the Spanish mass press coverage of ‘jihadist terrorist’ attacks in contemporary Spain. Drawing upon a critical analysis of the ‘Spanish Transition to Democracy’ (1975–82) and ‘War on Terror ...
Yebra López, Carlos
core +1 more source
Spanish-American War photograph collection [DIGITAL CONTENT]
, 1898 This collection contains photographs related to Arkansans in the Spanish-American ...
Central Arkansas Library System. Butler Center for Arkansas Studies. (Little Rock, Ark.)
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