Results 51 to 60 of about 13,497,395 (308)
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
The judicialization of territorial politics in Brazil, Colombia and Spain [PDF]
This article explains how judicial review influences intergovernmental political dynamics in Brazil, Colombia and Spain. The argument is developed in light of two questions: how supreme courts have established themselves as pivotal institutions for ...
Helder Ferreira do Vale
doaj
Junaci našeg doba: Lik narko-bosa u kolumbijskim telenovelama
U ovom radu se razmatra prikaz lika narko-bosa u kolumbijskim telenovelama. Dok zvanični diskurs tretira narko-bosa kao oličenje zla i svireposti, osobu koja podriva jedno (tobože) zdravo društveno telo, ove serije ga predstavljaju kao model socijalne ...
Diana Palaversich
doaj +1 more source
Subject pronoun expression (SPE) in Spanish has been widely studied across monolingual and bilingual varieties, showing a consistent effect of functional predictors.
Ana de Prada Pérez
doaj +1 more source
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
This study categorizes the 3,136 papers presented at the annual meetings of the Association for Spanish and Portuguese Historical studies from 1970 through 2017 according to the following criteria: temporal focus, geographic focus, themes, and sub-themes.
Phillips, Carla Rahn
core
Searching for a Common Place: Thoughts on Crisis, Marginality, and Social Change
This essay describes our neoliberal moment of crisis as a displacement of meaning regarding the more established notions of margin-center. Our times paradoxically ‘unite’ in that we are unwittingly governed by a financial logic that privileges personal ...
Txetxu Aguado, Annabel Martín
doaj +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Felipe Fernández-Armesto recounts a wonderful anecdote at the start of Our America: A Hispanic History of the United States (2014). Standing before a room of young cadets at the Air Force Academy in Colorado Springs, Fernández-Armesto invited audience ...
Saenz, Charles Nicholas
core

