Results 61 to 70 of about 287,769 (266)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Animación y música en los videoclips del Studio Ghibli

Revista Mediterránea de Comunicación, 2017
Este artículo analiza los videoclips animados creados por el Studio Ghibli, un reconocido estudio de animación japonés. El objetivo principal de este análisis es doble: por un lado se pretende establecer qué técnicas de animación se utilizan y cómo se ...
Francisco-Javier López-Rodríguez
doaj  

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Traduction économique en français et en espagnol ou comment rentabiliser le réseau Internet par le biais de corpus (méthodes et applications) [PDF]

Çédille: Revista de Estudios Franceses, 2013
Au sujet de Daniel Gallego Hernández, Traducción económica y corpus: del concepto a la concordancia. Aplicación al francés y al español (Alicante, Publicaciones de la Universidad de Alicante, 2012. 372 pp. ISBN: 978-84-9717-215-8).
Danielle Dubroca Galin
doaj  

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

On Teaching the History of California Spanish to HLL using Siri: Methodology and Procedures

Journal of New Approaches in Educational Research, 2016
This article reports results from a study in which two groups of college level students were exposed to interactions with Apple’s Siri in order to foster dialogue about their dialectal features.
Covadonga Lamar Prieto
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Heritage languages and socialization: an introduction

Journal of World Languages, 2023
Moreno-Fernández Francisco, Lamas Óscar Loureda   +1 more
doaj   +1 more source

The queer effect of matrilineal genealogies in Pedro Almodóvar's 'Todo sobre mi madre' (1999)

2i Revista de Estudos de Identidade e Intermedialidade
How can alternative kinship formations begin to challenge heteronormative and patriarchal family structures? Matrilineal genealogies are not subject to the limitations of patriarchal lineages.
McKenna Middleton
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source