Results 51 to 60 of about 1,498,758 (311)
Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga +2 more
wiley +1 more source
Biogenic CaCO3 microparticles obtained from oyster shells Crassostrea gigas were used as starting material for synthesizing Co2+, Mg2+ and Mn2+-doped apatite nano-submicroparticles, through a one-step hydrothermal conversion. The conversion was completed
Sandra María Cano-Plá +11 more
doaj +1 more source
The judicialization of territorial politics in Brazil, Colombia and Spain [PDF]
This article explains how judicial review influences intergovernmental political dynamics in Brazil, Colombia and Spain. The argument is developed in light of two questions: how supreme courts have established themselves as pivotal institutions for ...
Helder Ferreira do Vale
doaj
Searching for a Common Place: Thoughts on Crisis, Marginality, and Social Change
This essay describes our neoliberal moment of crisis as a displacement of meaning regarding the more established notions of margin-center. Our times paradoxically ‘unite’ in that we are unwittingly governed by a financial logic that privileges personal ...
Txetxu Aguado, Annabel Martín
doaj +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Developing indicators to measure Technology Institutes` performance [PDF]
Technology institutes (TIs) are non-profit innovation and technology organisations aimed to encourage competitiveness of firms. They are a key organisation in the Spanish National Innovation System because of their size and closeness to the productive ...
Barge, A., Modrego, Aurelia, Núñez, R.
core +2 more sources
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
First-grade Latino English language learners' performance on story problems in spanish versus english [PDF]
To explore whether teaching English Language Learners (ELLs) with an emphasis on English story problem is appropriate, we compared the performance of a group of Latino first graders when working in Spanish and in English on two equivalent sets of story ...
Ambrose, Rebecca, Molina, Marta
core +4 more sources
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Este artículo analiza la Conquista Espiritual do Oriente de Fr. Paulo da Trindade, obra mayor de la cronística franciscana portuguesa, escrita en Goa en la década de 1630.
Zoltán Biedermann
doaj +1 more source

