Results 81 to 90 of about 1,593 (185)

Kininase I drives angiotensin II‐induced hypertension through activation of the bradykinin B1 receptor

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Kininase I, comprising carboxypeptidase N (CPN) and carboxypeptidase M, regulates kinin activity and is up‐regulated during injury, inflammation and immune activation. Under these conditions, kininase I converts bradykinin and kallidin into des‐Arg kinins, primary endogenous agonists of the bradykinin B1 receptor (R ...
Acacia White, Drew Theobald, Alexandra Johnston, David A. Tulis, Johanna Hannan, Srinivas Sriramula   +5 more
wiley   +1 more source

Premium Intraocular Lens Selection in Patients With Glaucoma: A Clinical Review

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Glaucoma frequently coexists with cataract, but glaucomatous functional loss, ocular‐surface disease, anatomical abnormalities, and treatment‐related refractive variability may reduce tolerance of premium intraocular lenses. This narrative review critically appraises evidence relevant to lens selection in glaucoma. Central visual‐field status,
Zhihao Liu, Yajuan Zheng, Mingxuan Wang, Jing Zhao   +3 more
wiley   +1 more source

Dual-Branch Transformer–CNN Fusion for Enhanced Cloud Segmentation in Remote Sensing Imagery

Applied Sciences
Cloud coverage and obstruction significantly affect the usability of remote sensing images, making cloud detection a key prerequisite for optical remote sensing applications.
Shengyi Cheng, Hangfei Guo, Hailei Wu, Xianjun Du   +3 more
doaj   +1 more source

Disparities in Access to Revascularization: Evidence from New York

Health Equity, 2019
Purpose: To quantify and compare citywide disparities in the performance of coronary revascularization procedures in New York residents diagnosed with ischemic heart disease (IHD) by the characteristics of the patients and their neighborhood of residence
Michael K. Gusmano, Daniel Weisz, Catherine Allende, Victor G. Rodwin   +3 more
doaj   +1 more source

Human Embryonic Stem Cell‐Derived Immunity‐And‐Matrix‐Regulatory Cells Attenuate Pulmonary Fibrosis via MMP1‐Mediated Collagen Degradation

Cell Proliferation, EarlyView.
Human embryonic stem cell‐derived Immunity‐and‐Matrix‐Regulatory Cells (IMRCs) effectively attenuate pulmonary fibrosis by secreting Matrix Metalloproteinase‐1 (MMP1), which directly degrades excess collagen I in the extracellular matrix. By directly degrading collagen I, IMRCs reverse ECM stiffness, suppress myofibroblast activation, and promote a ...
Zhongwen Li, Dingyun Song, Faguo Sun, Licheng Song, Bin An, Tingting Gao, Jingjing Liu, Kan Zhang, Kaidi Liu, Kaiwei Wu, Yajing Li, Yi Yang, Yaru Liu, Ruofan Su, Zai Wang, Tiemei Zhao, Huaiyong Chen, Li Xiao, Liang Peng, Liu Wang, Wei Li, Lixin Xie, Jie Hao, Huaping Dai, Jun Wu   +24 more
wiley   +1 more source

The prediction of good physicians for prospective diagnosis using data mining

Informatics in Medicine Unlocked, 2018
This work provides a predictive model for selecting the most appropriate health care practitioners, particularly physicians, to diagnose a patient. In the context of a multidisciplinary diagnosis, this paper provides a data mining model to identify a ...
Nfongourain Mougnutou Rémy, Tekinzang Tedondjio Martial, Tayou Djamegni Clémentin   +2 more
doaj   +1 more source

Elevated IL‐4 and IL‐13 Expression in Hailey‐Hailey Disease: Evidence for Th2‐Mediated Pathogenesis and Targeted Treatment

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Hailey‐Hailey disease (HHD) is a rare autosomal dominant blistering disorder caused by mutations in the ATP2C1 gene, which impair keratinocyte adhesion through disrupted calcium signaling. While traditionally considered a structural defect, recent studies suggest that Th2‐mediated inflammation may exacerbate disease pathology ...
Simonetta I. Gaumond, Victoria Soto, Beatriz Abdo Abujamra, Franco Rongioletti, John A. McGrath, Ivan Jozic, Paolo Romanelli   +6 more
wiley   +1 more source

Repositioning Non‐Ablative Fractional Lasers ‐ Molecular and Histological Insights from a scoping review

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Near‐infrared non‐ablative fractional lasers (NAFL) are established for skin rejuvenation and scar treatment and have attracted interest for their expanding therapeutic potential. This scoping review aims to revisit and reposition NAFL within a fluence‐dependent continuum of tissue modulation, based on evidence from 27 studies of lasers ...
Guy Erlich, Uwe Paasch, Kevin Jacobsen, Merete Haedersdal, Uffe Høgh Olesen   +4 more
wiley   +1 more source

Generics favor stability

Mind &Language, EarlyView.
Humans seek to predict, explain, and control their environments. Generalizations—like those expressed by “children like candy” and “cigarettes cause cancer”—provide one resource to facilitate these tasks. We develop a proposal tying the acceptability judgments of generics to the psychological functions of generalizations.
Katherine Ritchie, Ny Vasil
wiley   +1 more source

SpaRCS: Recovering low-rank and sparse matrices from compressive measurements

, 2011
We consider the problem of recovering a matrix M that is the sum of a low-rank matrix L and a sparse matrix S from a small set of linear measurements of the form y = A(M) = A(L + S).
Andrew E. Waters, Aswin C. Sankaranarayanan, Richard G. Baraniuk   +2 more
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