Results 251 to 260 of about 93,971 (359)

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

open access: yesChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel   +5 more
wiley   +1 more source

Technological Properties of Biocomposites Produced With Agro‐Industrial Castor Waste Applicable in the Thermal Insulation of Buildings

open access: yesPolymer Composites, EarlyView.
Biocomposites produced with agro‐industrial waste from castor hulls and pinewood bonded with urea‐formaldehyde adhesive, intended for application as thermal insulation in buildings. ABSTRACT The production of composite particleboards with agricultural waste has been the focus of many studies that aim to address environmental problems due to waste ...
Thamirys Andrade Lopes   +7 more
wiley   +1 more source

Optimizing Processing and Formulation Strategies for Enhanced Thermal and Chemical Stability of Meltblown Polyphenylene Sulfide Nonwovens

open access: yesPolymer Engineering &Science, EarlyView.
PPS/PEI alloy fibers fabricated via meltblowing exhibit enhanced thermal stability with less than 10% shrinkage at 180°C, superior chemical resistance, and a high LOI of 34. ABSTRACT Polyphenylene sulfide (PPS) meltblown nonwovens are attractive for high‐performance filtration and protective applications owing to their intrinsic chemical resistance ...
Yi‐Cang Lai   +4 more
wiley   +1 more source

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