Results 21 to 30 of about 55,467 (261)

Electronic conduction in La-based perovskite-type oxides

Science and Technology of Advanced Materials, 2015
A systematic study of La-based perovskite-type oxides from the viewpoint of their electronic conduction properties was performed. LaCo0.5Ni0.5O3±δ was found to be a promising candidate as a replacement for standard metals used in oxide electrodes and ...
Hisashi Kozuka, Kazushige Ohbayashi, Kunihito Koumoto   +2 more
doaj   +1 more source

Direct Ink Writing Technology (3D Printing) of Graphene-Based Ceramic Nanocomposites: A Review

Nanomaterials, 2020
In the present work, the state of the art of the most common additive manufacturing (AM) technologies used for the manufacturing of complex shape structures of graphene-based ceramic nanocomposites, ceramic and graphene-based parts is explained.
Nestor Washington Solís Pinargote, Anton Smirnov, Nikita Peretyagin, Anton Seleznev, Pavel Peretyagin   +4 more
doaj   +1 more source

Intravitreal AAV vector delivery induces integrin-dependent ocular inflammation, complement activation, and antiviral and DNA damage responses

Frontiers in Immunology
BackgroundIntravitreal delivery of adeno-associated virus (AAV) vectors offers a promising, minimally invasive strategy for retinal gene therapy, but remains limited by dose-dependent intraocular inflammation. Corticosteroid therapy, the current standard
Helena Costa-Verdera, Helena Costa-Verdera, Deepa Jamwal, Emily Fabyanic, Ariel Hippen, Madeleine Salvatore, Aiping Du, Anna Majowicz, David Markusic, Jon E. Chatterton, Virginia Haurigot, Klaudia Kuranda   +11 more
doaj   +1 more source

Effect of Milling Conditions on the Microstructural Design in Aluminum Based Alloy Fabricated by SPS

Metals, 2019
In this work, aluminum-based alloys were mechanically alloyed by various doping elements followed by spark plasma sintering. Three different mixing methods were studied. First, all elemental powders were mixed for 24 h. In the second and the third method,
Anton Smirnov, Ekaterina Kuznetsova, Yuri Pristinskiy, Pavel Podrabinnik, Alexander Mironov, Iosif Gershman, Pavel Peretyagin   +6 more
doaj   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

A novel transcutaneous auricular neurostimulation electrode configuration for treatment of heavy menstrual bleeding: an open-label trial

Bioelectronic Medicine
Background Electrical stimulation of the cervical vagus nerve reduces traumatic blood loss in models of soft tissue injury. This pathway, termed the neural tourniquet, can be accessed with a transcutaneous auricular neurostimulation (tAN) targeting vagus
Christopher J. Czura, Angela C. Weyand, Maureen K. Baldwin, Michael Recht, Caroline G. Benner, Kimiko Harada, Brooke L. Wade, Meghan Luellen, Michael J. Darrow, Melanie A. McWade, Alejandro Covalin, Navid Khodaparast   +11 more
doaj   +1 more source

Inhibition of IFNAR-JAK signaling enhances tolerability and transgene expression of systemic non-viral DNA delivery

Molecular Therapy: Nucleic Acids
Lipid nanoparticles (LNPs) have demonstrated significant therapeutic value for non-viral delivery of mRNA and siRNA. While there is considerable interest in utilizing LNPs for delivering DNA (DNA-LNPs) to address a broad range of genetic disorders, acute
Sujata Senapati, Thais B. Bertolini, Michael A. Minnier, Mustafa N. Yazicioglu, David M. Markusic, Rui Zhang, Joan Wicks, Ali Nahvi, Roland W. Herzog, Matthew C. Walsh, Pedro J. Cejas, Sean M. Armour   +11 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source