Results 71 to 80 of about 513,547 (285)

Convex sparse PCA for unsupervised feature learning

open access: yes, 2016
© 2016 ACM. Principal component analysis (PCA) has been widely applied to dimensionality reduction and data preprocessing for different applications in engineering, biology, social science, and the like.
Chang, X   +4 more
core   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang   +8 more
wiley   +1 more source

Sparse outlier-robust PCA for multi-source data [PDF]

open access: yes
Sparse and outlier-robust Principal Component Analysis (PCA) has been a very active field of research recently. Yet, most existing methods apply PCA to a single dataset whereas multi-source data-i.e.
Filzmoser, Peter   +2 more
core   +5 more sources

Sparse PCA via Covariance Thresholding

open access: yesJ. Mach. Learn. Res., 2013
40 pages, 3 figures ...
Yash Deshpande, Andrea Montanari
openaire   +4 more sources

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

open access: yesAdvanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang   +11 more
wiley   +1 more source

Fast Randomized PCA for Sparse Data

open access: yesCoRR, 2018
Principal component analysis (PCA) is widely used for dimension reduction and embedding of real data in social network analysis, information retrieval, and natural language processing, etc. In this work we propose a fast randomized PCA algorithm for processing large sparse data.
Xu Feng   +4 more
openaire   +4 more sources

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

open access: yesAdvanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray   +3 more
wiley   +1 more source

GSN-SPCA: Integrating graph-based sparsity and label-guided weighting for pathway-driven biomarker discovery

open access: yesArray
Sparse Principal Component Analysis (SPCA) is a widely used unsupervised model for genomic feature selection. However, the existing SPCA model still has significant deficiencies in long-pathway identification, biological interpretability, and model ...
Rui Miao   +6 more
doaj   +1 more source

Sparse HJ Biplot: A New Methodology via Elastic Net

open access: yesMathematics, 2021
The HJ biplot is a multivariate analysis technique that allows us to represent both individuals and variables in a space of reduced dimensions. To adapt this approach to massive datasets, it is necessary to implement new techniques that are capable of ...
Mitzi Cubilla-Montilla   +3 more
doaj   +1 more source

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

open access: yesAdvanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu   +8 more
wiley   +1 more source

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