Results 91 to 100 of about 25,940 (257)

CauFinder: Steering Cell‐State and Phenotype Transitions by Causal Disentanglement Learning

Advanced Science, EarlyView.
CauFinder combines causal disentanglement modeling and network control to prioritize causal drivers of cell‐state transitions from observational transcriptomic data. The framework separates transition‐relevant signals from spurious associations, nominates intervention targets across biological and disease contexts, and identifies DAAM1 as an actionable
Chengming Zhang, Zexi Chen, Yuanxiang Miao, Zuolin Shen, Deyu Cai, Shijie Tang, Yun Xue, Weifeng Guo, Hongbin Ji, Jian Liu, Kazuyuki Aihara, Luonan Chen   +11 more
wiley   +1 more source

Illumination and expression robust face recognition using collaboration of double-dictionary's sparse representation-based classification

Dianxin kexue, 2017
A face recognition method named WT-CSRC was proposed by using wavelet transform (WT) and a collaboration of double-dictionary's sparse representation-based classification (CSRC).
Fei GONG, Wei JIN, Keqing ZHU, Randi FU, Yan CAO   +4 more
doaj   +2 more sources

Super-sparse principal component analyses for high-throughput genomic data

BMC Bioinformatics, 2010
Background Principal component analysis (PCA) has gained popularity as a method for the analysis of high-dimensional genomic data. However, it is often difficult to interpret the results because the principal components are linear combinations of all ...
Lee Youngjo, Lee Woojoo, Lee Donghwan, Pawitan Yudi   +3 more
doaj   +1 more source

Condition‐Associated Pattern Extraction and Recovery From Multi‐Condition Single‐Cell RNA‐seq Data With CAPER

Advanced Science, EarlyView.
Decoupling biological signals from unwanted variation in multi‑condition single‑cell RNA sequencing data remains challenging. CAPER disentangles condition‑associated biological effects from sample heterogeneity through matrix factorization, producing interpretable latent factors and a batch‑corrected expression matrix.
Ye Li, Jin Ning, An Wang, Minxi Shi, Yuanze Chen, Guoliang Liu, Shiquan Sun   +6 more
wiley   +1 more source

A Geometric Dictionary Learning Based Approach for Fluorescence Spectroscopy Image Fusion

Applied Sciences, 2017
In recent years, sparse representation approaches have been integrated into multi-focus image fusion methods. The fused images of sparse-representation-based image fusion methods show great performance.
Zhiqin Zhu, Guanqiu Qi, Yi Chai, Penghua Li   +3 more
doaj   +1 more source

A Blood‐Derived Double‐Network Hydrogel with Robust Wet Adhesion for Keratinized Mucosa Regeneration via Neutrophil Phenotype Reprogramming and Mechanophysical Niche Modulation

Advanced Science, EarlyView.
The iPRF‐MA/Alg‐NHS/Lut@EGCG (PGAE) double‐network hydrogel achieves durable wet adhesion in the oral environment. It simultaneously reprograms neutrophils from NETosis to phagocytosis for biofilm clearance, and activates the FAK‐RhoA‐YAP mechanotransduction pathway in gingival fibroblasts to drive extracellular matrix remodeling, thereby promoting ...
Sicong Ren, Xinting Yang, Jingxia Chen, Yihan Wang, Jian Feng, Jing Zhou, Jiaxin Luo, Jingjie Zhai, Quan Lin, Yanmin Zhou   +9 more
wiley   +1 more source

The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly

Advanced Science, EarlyView.
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie, Sibing Yi, Xinle Lin, Shen Zhang, Weili Wang, Shimin Yuan, Lanlan Meng, Yong Li, Chen Tan, Chunjia Wei, Yanyan Yu, Yaoqiong Liang, Huan Zhang, Liang Hu, Guangxiu Lu, Wenbin He, Qianjun Zhang, Juan Du, Ge Lin, Chaofeng Tu, Yue‐Qiu Tan   +20 more
wiley   +1 more source

Machine‐Learning Framework for Designing Stable Interfaces in All‐Solid‐State Lithium‐Ion Batteries

Advanced Science, EarlyView.
A data‐driven strategy is developed to discover coating materials for all‐solid‐state lithium batteries. Using calculations of interfacial reactivity, unsupervised pattern recognition, and machine‐learning prediction, the study identifies low‐reactivity compositional patterns and screens new lithium‐based oxide and polyanion candidates, extending ...
Sehyeok Park, Myeongcho Jang, Hun‐Gi Jung, Kyung Yoon Chung, Seungho Yu   +4 more
wiley   +1 more source

Quartic Quantum Speedups for Planted Inference

Physical Review X
We describe a quantum algorithm for the Planted Noisy kXOR Problem (also known as Sparse Learning Parity with Noise) that achieves a nearly quartic (fourth-power) speedup over the best known classical algorithm while using exponentially less space.
Alexander Schmidhuber, Ryan O’Donnell, Robin Kothari, Ryan Babbush   +3 more
doaj   +1 more source

Ensemble Principal Component Analysis

IEEE Access
Efficient representations of data are essential for processing, exploration, and human understanding, and Principal Component Analysis (PCA) is one of the most common dimensionality reduction techniques used for the analysis of large, multivariate ...
Olga Dorabiala, Aleksandr Y. Aravkin, J. Nathan Kutz   +2 more
doaj   +1 more source