Results 61 to 70 of about 3,880 (235)

Temporal discrimination: Mechanisms and relevance to adult-onset dystonia [PDF]

, 2017
Temporal discrimination is the ability to determine that two sequential sensory stimuli are separated in time. For any individual, the temporal discrimination threshold (TDT) is the minimum interval at which paired sequential stimuli are perceived as ...
Beck, Rebecca, Conte, Antonella, Hutchinson, Michael, Killian, Owen, Mcgovern, Eavan M., Narasimham, Shruti, O'Riordan, Sean, Reilly, Richard B.   +7 more
core   +1 more source

High-throughput mutational analysis of TOR1A in primary dystonia

BMC Medical Genetics, 2009
Background Although the c.904_906delGAG mutation in Exon 5 of TOR1A typically manifests as early-onset generalized dystonia, DYT1 dystonia is genetically and clinically heterogeneous.
Truong Daniel D, Tarsy Daniel, Simon David K, Hedera Peter, Uitti Ryan J, Wszolek Zbigniew K, Batish Sat, Blitzer Andrew, Paniello Randal C, Karimi Morvarid, Tabbal Samer D, Racette Brad A, Perlmutter Joel S, Bastian Robert W, Xiao Jianfeng, Frei Karen P, Pfeiffer Ronald F, Gong Suzhen, Zhao Yu, LeDoux Mark S   +19 more
doaj   +1 more source

Long‐Term Safety and Efficacy of Repeat Treatments with DaxibotulinumtoxinA in Cervical Dystonia: Results from the ASPEN‐Open‐Label Study

Movement Disorders Clinical Practice, EarlyView.
ABSTRACT Background DaxibotulinumtoxinA (DAXI), a novel botulinum neurotoxin (BoNT) formulation, was shown to be safe, effective, and long‐lasting in the treatment of cervical dystonia (CD) over one treatment cycle in the phase 3, randomized, placebo‐controlled ASPEN‐1 trial.
Peter McAllister, Atul T. Patel, Marta Banach, Aaron Ellenbogen, Jaroslaw Slawek, Sebastian Paus, Hyder A. Jinnah, Virgilio Evidente, Todd M. Gross, Rashid Kazerooni, Conor J. Gallagher, David A. Hollander   +11 more
wiley   +1 more source

An Auditory-Perceptual and Pupillometric Study of Vocal Strain and Listening Effort in Adductor Spasmodic Dysphonia

Applied Sciences, 2020
This study evaluated ratings of vocal strain and perceived listening effort by normal hearing participants while listening to speech samples produced by talkers with adductor spasmodic dysphonia (AdSD).
Mojgan Farahani, Vijay Parsa, Björn Herrmann, Mason Kadem, Ingrid Johnsrude, Philip C. Doyle   +5 more
doaj   +1 more source

Computer Vision Technologies in Movement Disorders: A Systematic Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Evaluation of movement disorders primarily relies on phenomenology. Despite refinements in diagnostic criteria, the accuracy remains suboptimal. Such a gap may be bridged by machine learning and video technology, which permit objective, quantitative, non‐invasive motor analysis.
Pasquale Maria Pecoraro, Luca Marsili, Alberto J. Espay, Matteo Bologna, Lazzaro di Biase   +4 more
wiley   +1 more source

Distribution of neuromuscular junctions in laryngeal and syringeal muscles in vertebrates [PDF]

, 2006
Vertebrates are capable of producing a variable sound spectrum. In mammals, lissamphibia, and reptiles, the larynx is the vocal organ responsible for sound production, whereas in birds it is produced by the syrinx, an avian organ located at the base of
Ana Valle-Fernandes, Armando Almeida, Bielamowicz, Blitzer, Boyd, Castellanos, Fitch, Fitch, George, Greene, Gunter, Harris, Hartdegen, Hoese, Inagi, Kardong, Kelley, Koelle, Manuel Lima-Rodrigues, Marler, Marler, Maronian, McClelland, Mergell, Nottebohm, Pais-Clemente, Pepperberg, Podos, Pontes, Périé, Rosen, Rossi, Rossi, Rui Nunes, Sacchi, Sheppert, Storer, Tisch, Vicario, White, Wild, Williams, Young   +42 more
core   +1 more source

Successful step-by-step diagnosis and management of expiratory central airway collapse

Respiratory Medicine Case Reports, 2023
A 45-year-old woman with recurrent dyspnea for 40 years was previously diagnosed with bronchial asthma and spasmodic dysphonia. On admission, the patient was diagnosed with expiratory central airway collapse (ECAC) due to expiratory dynamic airway ...
Yasuhiro Matsumura, Kimihiko Kobayashi, Kentaro Kitano, Masaaki Nagano, Masaaki Sato   +4 more
doaj  

Exploring Neurophysiological Mechanisms and Treatment Efficacies in Laryngeal Dystonia: A Transcranial Magnetic Stimulation Approach

Brain Sciences, 2023
Laryngeal dystonia (LD), known or termed as spasmodic dysphonia, is a rare movement disorder with an unknown cause affecting the intrinsic laryngeal muscles.
Maja Rogić Vidaković, Joško Šoda, Joshua Elan Kuluva, Braco Bošković, Krešimir Dolić, Ivana Gunjača   +5 more
doaj   +1 more source

Subjective Well‐Being and Its Predictors in Parkinson's Disease and Dystonia: A Comparative Study

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Quality of life (QoL) is a commonly used outcome measure in people with chronic neurological diseases (CND). As valuable as QoL is, it does not take into account aspects of subjective well‐being (SWB) such as subjective happiness, meaning in life, life satisfaction and hope; all constructs that are considered central to well‐being ...
Suzette Shahmoon, Dejan Georgiev, Paul Jarman, Kailash Bhatia, Patricia Limousin, Marjan Jahanshahi   +5 more
wiley   +1 more source

Application of integrated perturbation index and articulatory precision index in patients with spasmodic dysphonia [PDF]

, 2014
La disfonía espasmódica es un desorden vocal severo caracterizado por una interrupción involuntaria de la fonación, denominada también distonía focal laríngea.
Gurlekian, Jorge Alberto, Sigal, Liliana
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