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2002
Infantile spasms (West's Syndrome) is a syndrome which includes a peculiar type of epileptic seizure, usually hypsarrhythmia and in the majority of people, psychomotor retardation. It remains poorly understood and despite modern imaging techniques an underlying cause is often not found. Little is known about their pathophysiological basis and treatment
E, Hancock, J P, Osborne, P, Milner
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Infantile spasms (West's Syndrome) is a syndrome which includes a peculiar type of epileptic seizure, usually hypsarrhythmia and in the majority of people, psychomotor retardation. It remains poorly understood and despite modern imaging techniques an underlying cause is often not found. Little is known about their pathophysiological basis and treatment
E, Hancock, J P, Osborne, P, Milner
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The latest on infantile spasms
Current Opinion in Neurology, 2005This article reviews the most significant advances in the field of infantile spasm during the past year, with emphasis on best practise for treatment, and on some new etiological genetic and metabolic causes for the spasms, and new advances in the knowledge of tuberous sclerosis.Up-to-date information comparing corticotrophin, oral steroids and ...
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Pathophysiology of Infantile Spasms
2002Infantile spasms--seen in West's Syndrome--are often associated with cortical abnormalities. The spasms themselves, however, appear to be generated subcortically. Dr. Chugani reviews the clinical data related to the pathophysiology of infantile spasms and proposes a hypothesis which involves both cortical and subcortical mechanisms.
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Ugeskrift for laeger, 2021
Infantile spasms (IS) is a severe developmental and epileptic encephalopathy, occurring mainly in children aged 3-18 months. IS have multiple aetiologies, and the treatment differs accordingly. Early diagnosis and treatment may improve the outcome, but many patients are initially misdiagnosed.
Marie, Préel +3 more
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Infantile spasms (IS) is a severe developmental and epileptic encephalopathy, occurring mainly in children aged 3-18 months. IS have multiple aetiologies, and the treatment differs accordingly. Early diagnosis and treatment may improve the outcome, but many patients are initially misdiagnosed.
Marie, Préel +3 more
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JAMA, 1967
SINCE West 1 vividly described the syndrome of infantile spasms with progressive mental deterioration 125 years ago, the condition has been known under a variety of names, such as nodding spasms, salaam seizures, jack-knife seizures, "lightning majors," and massive myoclonic epilepsy.
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SINCE West 1 vividly described the syndrome of infantile spasms with progressive mental deterioration 125 years ago, the condition has been known under a variety of names, such as nodding spasms, salaam seizures, jack-knife seizures, "lightning majors," and massive myoclonic epilepsy.
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INFANTILE SPASMS AND HYPSARRHYTHMIA
The Lancet, 1959B D, BOWER, P M, JEAVONS
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Lamotrigine in infantile spasms
The Lancet, 1994Veggiotti P, Cieuta C, Rex E, Dulac O.
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