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Vigabatrin for Infantile Spasms
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2011Infantile spasms describe a pediatric epilepsy syndrome characterized by frequent clusters of brief symmetric muscle contractions; the condition is often associated with developmental delay. When infantile spasms are accompanied by hypsarrhythmia on electroencephalogram, the condition is labeled West syndrome.
Kimberly A, Pesaturo +2 more
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The latest on infantile spasms
Current Opinion in Neurology, 2005This article reviews the most significant advances in the field of infantile spasm during the past year, with emphasis on best practise for treatment, and on some new etiological genetic and metabolic causes for the spasms, and new advances in the knowledge of tuberous sclerosis.Up-to-date information comparing corticotrophin, oral steroids and ...
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2002
Infantile spasms (West's Syndrome) is a syndrome which includes a peculiar type of epileptic seizure, usually hypsarrhythmia and in the majority of people, psychomotor retardation. It remains poorly understood and despite modern imaging techniques an underlying cause is often not found. Little is known about their pathophysiological basis and treatment
E, Hancock, J P, Osborne, P, Milner
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Infantile spasms (West's Syndrome) is a syndrome which includes a peculiar type of epileptic seizure, usually hypsarrhythmia and in the majority of people, psychomotor retardation. It remains poorly understood and despite modern imaging techniques an underlying cause is often not found. Little is known about their pathophysiological basis and treatment
E, Hancock, J P, Osborne, P, Milner
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JAMA, 1967
SINCE West 1 vividly described the syndrome of infantile spasms with progressive mental deterioration 125 years ago, the condition has been known under a variety of names, such as nodding spasms, salaam seizures, jack-knife seizures, "lightning majors," and massive myoclonic epilepsy.
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SINCE West 1 vividly described the syndrome of infantile spasms with progressive mental deterioration 125 years ago, the condition has been known under a variety of names, such as nodding spasms, salaam seizures, jack-knife seizures, "lightning majors," and massive myoclonic epilepsy.
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Pathophysiology of Infantile Spasms
2002Infantile spasms--seen in West's Syndrome--are often associated with cortical abnormalities. The spasms themselves, however, appear to be generated subcortically. Dr. Chugani reviews the clinical data related to the pathophysiology of infantile spasms and proposes a hypothesis which involves both cortical and subcortical mechanisms.
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INFANTILE SPASMS AND HYPSARRHYTHMIA
The Lancet, 1959B D, BOWER, P M, JEAVONS
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Current management of infantile cataracts
Survey of Ophthalmology, 2022Phoebe D Lenhart, Scott R Lambert
exaly