Intrathecal Baclofen in Hereditary Spastic Paraparesis [PDF]
Introduction: Treatment with intrathecal baclofen (ITB) is a therapeutic option in the management of severe spasticity in patients with hereditary spastic paraparesis (HSP).
Elke Pucks-Faes +8 more
doaj +4 more sources
Reversible spastic paraparesis
Ananthanarayanan Kasinathan +4 more
doaj +4 more sources
Tropical spastic paraparesis in Northeastern Brazil [PDF]
Ten possible cases of tropical spastic paraparesis (TSP) in Northeastern Brazil (Ceará) are presented. They show the typical symptoms and signs of TSP consisting of weakness of the lower limbs, spastic gait, hiperreflexia, bladder dysfunction and ...
C. M. de Castro Costa +4 more
doaj +6 more sources
"Ear of the Lynx" Sign in Hereditary Spastic Paraparesis (HSP) 76. [PDF]
Hereditary Spastic Paraparesis (HSP) are a group of genetically inherited disorders, clinically and genetically heterogenous and characterized by degeneration of corticospinal tracts, manifesting with progressive spasticity and lower limbs weakness. Most
Agarwal A +6 more
europepmc +2 more sources
Neuroimmunology of Human T-Lymphotropic Virus Type 1-Associated Myelopathy/Tropical Spastic Paraparesis [PDF]
Human T-lymphotropic virus type 1 (HTLV-1) is the etiologic agent of both adult T-cell leukemia/lymphoma and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Satoshi Nozuma, Steven Jacobson
openalex +2 more sources
Mortality and risk of progression to adult T cell leukemia/lymphoma in HTLV-1–associated myelopathy/tropical spastic paraparesis [PDF]
Significance HTLV-1 manifests many diseases, which cause morbidity and mortality in 5∼10% of infected individuals, including the fatal adult T cell leukemia/lymphoma (ATLL) and debilitating myelopathy (HAM/TSP).
Misako Nagasaka +20 more
openalex +2 more sources
Early presentation of spastic paraparesis in individuals carrying PSEN1 mutations: a clinical and genetic analysis [PDF]
Background Mutations in the presenilin 1 gene (PSEN1) are well-known causes of early-onset familial Alzheimer’s disease, but they can also present with atypical phenotypes such as pure spastic paraparesis.
Kang-Yang Jih +7 more
doaj +2 more sources
Early-Onset HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis
Background: Vertical transmission of HTLV-1 could lead to the early development of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). This significantly affects quality of life and increases morbimortality.
Alvaro Schwalb +7 more
doaj +2 more sources
Tropical spastic paraparesis – anesthetic approach
Introduction: HTLV-1 infection is endemic in Japan, Caribbean, Africa, and South America. It is transmitted from mother to child, sexual contact, blood transfusions, or sharing needles.
Margarida Rodrigues +2 more
doaj +5 more sources
Spastic Paraparesis Following Cocaine Inhalation [PDF]
Cocaine use is reaching epidemic proportions in the UK and the consequences are a number of debilitating effects. Strokes may result from a number of mechanisms related to cocaine use.
Henry Oluwasefunmi Savage +2 more
doaj +3 more sources

