Effect of pulsed methylprednisolone on pain, in patients with HTLV-1-associated myelopathy [PDF]
, 2016 HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is an immune mediated myelopathy caused by the human T-lymphotropic virus type 1 (HTLV-1). The efficacy of treatments used for patients with HAM/TSP is uncertain.
Adonis, A +8 more
core +1 more source
Novel OPA1 mutation featuring spastic paraparesis and intestinal dysmotility
Molecular Genetics and Metabolism Reports, 2014 A 58-year-old man with optic atrophy, spastic paraparesis, axonal sensorimotor peripheral neuropathy and intestinal dysmotility harbors a novel heterozygous missense mutation in the mitochondrial import signal peptide of OPA1.
Mohamed Kazamel +2 more
doaj +1 more source
From cirrhosis to paraparesis [PDF]
Romanian Journal of Neurology, 2019 We present the case of a 61-years-old male, diagnosed with liver cirrhosis, portal hypertension and type II diabetes mellitus, who developed bilateral signs of Parkinsonism, intention tremor and spastic paraparesis.
Ioan-Cristian Lupescu +4 more
doaj +1 more source
High prevalence of bronchiectasis is linked to HTLV-1-associated inflammatory disease. [PDF]
, 2015 BACKGROUND: Human T-lymphotropic virus type 1 (HTLV-1), a retrovirus, is the causative agent of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T-cell leukaemia/lymphoma (ATLL).
A Gessain +37 more
core +1 more source
A Fashi Lymphoproliferative Phenotype Reveals Non-Apoptotic Fas Signaling in HTLV-1-Associated Neuroinflammation [PDF]
, 2017 Human T-cell lymphotropic virus (HTLV)-1 was the first human retrovirus to be associated to cancer, namely adult T-cell leukemia (ATL), but its pathogenesis remains enigmatic, since only a minority of infected individuals develops either ATL or the ...
Anne Mieke Vandamme +18 more
core +1 more source
Early-Onset HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis
Pathogens, 2020 Background: Vertical transmission of HTLV-1 could lead to the early development of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). This significantly affects quality of life and increases morbimortality.
Alvaro Schwalb +7 more
doaj +1 more source
Diagnosis, investigation and management of hereditary spastic paraplegias in the era of next-generation sequencing. [PDF]
, 2014 The hereditary spastic paraplegias (HSPs) are a group of genetic conditions in which spastic paralysis of the legs is the principal clinical feature. This is caused by a relatively selective distal axonal degeneration involving the longest axons of the ...
Hensiek, Anke +2 more
core +2 more sources
Hepatic Myelopathy in a Patient with Decompensated Alcoholic Cirrhosis and Portal Colopathy
Case Reports in Hepatology, 2012 Cirrhotic or hepatic myelopathy is a rare neurological complication of chronic liver disease usually seen in adults and presents as a progressive pure motor spastic paraparesis which is usually associated with overt liver failure and a surgical or ...
Madhumita Premkumar +7 more
doaj +1 more source
Telomere Length, Proviral Load and Neurologic Impairment in HTLV-1 and HTLV-2-Infected Subjects. [PDF]
, 2016 Short or damaged telomeres have been implicated in degenerative conditions. We hypothesized that analysis of telomere length (TL) in human T-cell lymphotropic virus (HTLV) infection and HTLV-associated neuropathy might provide clues to the etiology of ...
Blackburn, Elizabeth +5 more
core +3 more sources
Myelitis due to Neurobrucellosis with Normal MR Findings
Haseki Tıp Bülteni, 2014 Neurobrucellosis is an uncommon complication of brucellosis. The clinical features vary greatly and, tend to be chronic. Many laboratory procedures are usually employed in the diagnosis of neurobrucellosis. It is essential to perform serological tests in
Özlem Bizpınar Munis +3 more
doaj +1 more source