Early presentation of spastic paraparesis in individuals carrying PSEN1 mutations: a clinical and genetic analysis [PDF]
Alzheimer’s Research & TherapyBackground Mutations in the presenilin 1 gene (PSEN1) are well-known causes of early-onset familial Alzheimer’s disease, but they can also present with atypical phenotypes such as pure spastic paraparesis.
Kang-Yang Jih +7 more
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An Unexplained Case of Progressive Spastic Paraparesis in an Individual with Known DiGeorge Syndrome
Case Reports in Neurology, 2020 DiGeorge syndrome (22q11.2 deletion) is associated with several neurologic disorders including structural abnormalities involving brain and spine, movement disorders, and epilepsy.
Roshni Dhoot +3 more
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Magnetic resonance imaging for Human T-cell lymphotropic virus type 1 (HTLV1-) associated myelopathy/tropical spastic paraparesis patients: a systematic review [PDF]
Reviews in Clinical Medicine, 2015 Introduction: Human T-cell lymphotropic virus type 1 (HTLV-1) associated myelopathy/tropical spastic paraparesis is a chronic progressive neurologic disease which might be associated by brain and spinal cord atrophy and lesions.
Fariba Zemorshidi +2 more
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A rare case of adult-onset spastic paraparesis associated with Klinefelter syndrome [PDF]
BMC NeurologyReport The rare association of Klinefelter syndrome and the clinical presentation of a late onset chronic progressive spastic paresis. Clinical Presentation and Genetics An infertile, 61-year-old man, presented with late adult onset of gait problems ...
Louise Adams, Jan De Bleecker
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Lived Experience of Human T-cell Leukemia Virus type-1 -Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP): A Phenomenology Study [PDF]
Iranian Journal of Medical SciencesBackground: Human T-cell Leukemia Virus type-1 (HTLV-1) -associated myelopathy causes sufferers to experience changes in several aspects of their lives.
Malihe Davoudi +2 more
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Urodynamic findings and vibegron effects on neurogenic lower urinary tract dysfunction caused by human T‐cell leukemia virus type I‐associated myelopathy/tropical spastic paraparesis [PDF]
IJU Case ReportsIntroduction Human T‐cell lymphotropic virus type 1 infection can cause HTLV‐1‐associated myelopathy/tropical spastic paraparesis, characterized by spastic paralysis of both lower limbs. More than 90% of HAM/TSP patients show lower urinary tract symptoms
Tomoyuki Kumekawa +9 more
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IJU Case Reports, 2021 Introduction Neurogenic overactive bladder is a main feature of human T‐cell leukemia virus type 1‐associated myelopathy/tropical spastic paraparesis. We successfully performed intravesical onabotulinumtoxinA therapy for refractory neurogenic overactive ...
Tomohiro Matsuo +4 more
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Annals of Indian Academy of Neurology, 2021 Objectives: The objective of this study is to describe the clinical, biochemical, radiological, and genetic profile of patients presenting with progressive spastic paraparesis due to homocysteine remethylation pathway defect.
Hansashree Padmanabha +13 more
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A rare complication of cirrhosis: Hepatic myelopathy
Journal of Spinal Surgery, 2014 Introduction: Hepatic myelopathy is characterized by spastic paraparesis and minimal sensory abnormalities in patients with cirrhosis, particularly those with portosystemic shunts that have been created surgically or have occurred spontaneously ...
Sofiene Bouali +5 more
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The Barriers of Coping with HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis: A Content Analysis Study [PDF]
Journal of Evidence-Based Care, 2023 Background: HTLV-1-associated myelopathy is associated with constant stress, so it is very important to cope with this disease. To improve the coping of patients with this disease, it is necessary to deeply identify its barriers.Aim: The present study ...
Malihe Davoudi +2 more
doaj +1 more source