Results 31 to 40 of about 29,371 (197)

Early-Onset HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis

Pathogens, 2020
Background: Vertical transmission of HTLV-1 could lead to the early development of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). This significantly affects quality of life and increases morbimortality.
Alvaro Schwalb, Valeria Pérez-Muto, Rodrigo Cachay, Martín Tipismana, Carolina Álvarez, Fernando Mejía, Elsa González-Lagos, Eduardo Gotuzzo   +7 more
doaj   +1 more source

Hepatic Myelopathy in a Patient with Decompensated Alcoholic Cirrhosis and Portal Colopathy

Case Reports in Hepatology, 2012
Cirrhotic or hepatic myelopathy is a rare neurological complication of chronic liver disease usually seen in adults and presents as a progressive pure motor spastic paraparesis which is usually associated with overt liver failure and a surgical or ...
Madhumita Premkumar, Avishek Bagchi, Neha Kapoor, Ankit Gupta, Gaurav Maurya, Shubham Vatsya, Siddharth Kapahtia, Premashish Kar   +7 more
doaj   +1 more source

Myelitis due to Neurobrucellosis with Normal MR Findings

Haseki Tıp Bülteni, 2014
Neurobrucellosis is an uncommon complication of brucellosis. The clinical features vary greatly and, tend to be chronic. Many laboratory procedures are usually employed in the diagnosis of neurobrucellosis. It is essential to perform serological tests in
Özlem Bizpınar Munis, Mehmet Fevzi Öztekin, Tehran Aliyeva, Derya Bayrak   +3 more
doaj   +1 more source

Hepatic Myelopathy: A Rare Complication of Chronic Liver Failure Treated Conservatively Without Liver Transplantation

Annals of Internal Medicine: Clinical Cases
Hepatic myelopathy (HM) diagnosis requires the exclusion of other causes of spastic paraparesis and typically presents in the setting of recurrent hepatic encephalopathy.
Matthew Lynberg, Ishan Kirti, Nahar Saleh, Haider Naqvi   +3 more
doaj   +1 more source

Individual perception of environmental factors that influence lower limbs spasticity in inherited spastic paraparesis

, 2023
International audienceBackground: Phenotypic variability is a consistent finding in neurogenetics and therefore applicable to hereditary spastic paraparesis. Identifying reasons for this variability is a challenge.
Philippe Corcia, Anna Heinzmann, Corcia, Philippe, Fenu, Silvia, Alexandra Durr, Jean Benard, Ewenczyk, Claire, Mochel, Fanny, Durr, Alexandra, Pauline Lallemant-Dudek, Livia Parodi, Charles, Perrine, Heinzmann, Anna, Perrine Charles, Giulia Coarelli, Marie-Lorraine Monin, Fanny Mochel, Lallemant-Dudek, Pauline, Christel Depienne, Sophie Tezenas du Montcel, Silvia Fenu, Depienne, Christel, Claire Ewenczyk, Benard, Jean, Tezenas Du Montcel, Sophie, Coarelli, Giulia, Parodi, Livia, Monin, Marie-Lorraine   +27 more
core   +1 more source

Upregulation of hsa-miR-125b in HTLV-1 asymptomatic carriers and HTLV-1-associated myelopathy/tropical spastic paraparesis patients

Memorias do Instituto Oswaldo Cruz, 2012
The retrovirus human T lymphotropic virus type 1 (HTLV-1) promotes spastic paraparesis, adult T cell leukaemia and other diseases. Recently, some human microRNAs (miRNAs) have been described as important factors in host-virus interactions.
Larissa Deadame de Figueiredo Nicolete, Roberto Nicolete, Rodrigo Haddad, Rochele Azevedo, Fabíola Attié de Castro, Yuetsu Tanaka, Osvaldo Massaiti Takayanagui, Dimas Tadeu Covas, Simone Kashima   +8 more
doaj   +1 more source

Neurolathyrism in Sub‐Saharan Africa—Assessing the Neurotoxic Risks of Lathyrus sativus Amid Drought and Food Security Challenges

Food Safety and Health, EarlyView.
Representation of grass pea consumption in drought‐stricken sub‐Saharan Africa sustains nutrition, but excess β‐ODAP exposure due to multiple reasons triggers neurolathyrism, a progressive neurotoxic disorder. ABSTRACT Neurolathyrism is a progressive motor neuron disease due to the consumption of Lathyrus sativus (grass pea) over long periods.
Biruk Demisse Ayalew, Muhammad Umar, Pakeezah Tabasum, Maria Qadri, Talha Farooq, Eskeatnaf Yosef Getachew, Zemichael Getu Alemayehu, Eden Haile Hagos, Hailemariam Shimelis Gebeyehu, Hanna Tsehay Abebe, Nuradin Abdi Ali, David Chinaecherem Innocent, Temesgen Mamo Sharew   +12 more
wiley   +1 more source

Normal cholestanol in a genetically confirmed cerebrotendious xanthomatosis case presenting as neonatal jaundice

JPGN Reports, EarlyView.
Abstract Cerebrotendinous xanthomatosis (CTX) is a treatable genetic disorder associated with deficiency of the sterol 27‐hydroxylase enzyme (CYP27A1), important in bile acid synthesis. CTX may present in the newborn period as hepatic jaundice/cholestasis, that can resolve or can progress to fatal liver disease.
Andrea E. DeBarber, Maya Fowler, P. Barton Duell, Eric Dybbro   +3 more
wiley   +1 more source

Movement Disorders in Developmental and Epileptic Encephalopathies

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Monogenic developmental and epileptic encephalopathies (DEE) frequently feature co‐occurring movement disorders. Gene discovery has expanded epilepsy‐dyskinesia syndromes (EDS) from classic associations such as stereotypies in Rett syndrome to PRRT2‐related infantile seizures with paroxysmal dyskinesia and crouched gait in SCN1A ...
Shekeeb Mohammad, Darius Ebrahimi‐Fakhari, Hugo Morales‐Briceno   +2 more
wiley   +1 more source

Novel mutations in the ABCD1 gene caused adrenomyeloneuropathy in the Chinese population

Frontiers in Neurology, 2023
BackgroundAs a rare genetic disease, adrenomyeloneuropathy (AMN) is the most common adult phenotype of X-linked adrenoleukodystrophy (X-ALD). Mutations in the ABCD1 gene have been identified to cause AMN.MethodsWe applied clinical evaluation, laboratory ...
Raoli He, Raoli He, Jian Zhang, Jian Zhang, Tianwen Huang, Tianwen Huang, Guoen Cai, Guoen Cai, Zhangyu Zou, Zhangyu Zou, Qinyong Ye, Qinyong Ye, Qinyong Ye   +12 more
doaj   +1 more source