Results 51 to 60 of about 29,371 (197)

Retinal neurovascular alterations are associated with optic radiation microstructure in adrenomyeloneuropathy: A susceptibility separation MRI study

VIEW, EarlyView.
In a cross‐sectional cohort of 104 participants, 7 T susceptibility separation MRI and diffusion imaging were combined with retinal imaging and visual evoked potentials to characterize visual pathway involvement in adrenomyeloneuropathy (AMN). Absolute diamagnetic susceptibility, a myelin‐associated measure, and fractional anisotropy (FA) showed ...
Ronghao Li, Jun Li, Chongyi Li, Xingang Wang, Wenyu Zhou, Yangcheng Zou, Zhiming Zhen, Li Xiao, Na Liang, Zongxing Zou, Junru Yang, Hui Yang, Chunhua Fu, Weiqi Chen, Yuyu Chen, Chen Liu, Hongjiang Wei, Liang Tan   +17 more
wiley   +1 more source

Hyperhomocysteinemia due to MTHFR deficiency - A treatable metabolic causes of progressive spastic paraparesis not to be missed

Annals of Movement Disorders
Methylenetetrahydrofolate reductase (MTHFR) deficiency is a rare autosomal-recessive disorder of folate metabolism, presenting with neurological symptoms such as spastic paraparesis, cognitive impairment, and psychosis.
Kamalesh Tayade, Jivan Morey, Haresh Bharote, Dnyaneshwar Asole, Anil Venkitachalam   +4 more
doaj   +1 more source

Input Visualizations to Track Health Data by Older Adults with Multiple Chronic Conditions

Computer Graphics Forum, EarlyView.
Abstract Older adults living with multiple chronic conditions (MCC) can considerably benefit from collecting and reflecting on their health data. Many older adults collect their health data using various approaches, such as digital tools or handwritten notebooks.
Shri Harini Ramesh, Foroozan Daneshzand, Matteo Sotelo, Mahsa Sinaei, Fateme Rajabiyazdi   +4 more
wiley   +1 more source

Hepatic myelopathy as a rare but reversible neurological complication post transjugular intrahepatic portosystemic shunt (TIPS) insertion in liver cirrhosis

European Journal of Case Reports in Internal Medicine
Hepatic myelopathy is a rare but underrecognized complication of chronic liver disease characterized by pure motor, symmetric and spastic paraparesis without sphincter involvement.
Angela Zhu, Warren Clements, Robb Wesselingh, Natasha Janko   +3 more
doaj   +1 more source

Association of late onset spastic paraparesis and dementia: Probably an autosomal dominant form of complicated paraplegia

, 1997
The hereditary paraplegias are a heterogeneous group of genetic disorders characterized mainly by spastic paraparesis, which may be found as an isolated 'pure form' known as Strumpell-Lorrain syndrome, or associated with a wide group of other ...
Bernal-Beltran, M.D.P., García-Cruz, D., Hernandez, A., Lizcano-Gil, L.A.   +3 more
core   +1 more source

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source

Dorsolateral Cervical Cord T2 Hyperintensity in KIF1C‐Related Disease (Spastic Paraplegia 58): Two Long‐Duration Cases

Annals of Clinical and Translational Neurology
Pathogenic variants in KIF1C cause Spastic Paraplegia 58 (SPG58), typically presenting with cerebellar ataxia and spastic paraparesis. We report two unrelated patients with spastic paraparesis, cerebellar ataxia, and tremor. Whole‐exome sequence analysis
Akihiko Mitsutake, Masao Osaki, Takashi Matsukawa, Miho Osako, Chisen Takeuchi, Hiroyuki Ishiura, Jun Mitsui, Ryo Kurokawa, Harushi Mori, Yuji Takahashi, Jun Goto, Shoji Tsuji, Tatsushi Toda   +12 more
doaj   +1 more source

Hypermanganesemia in Children With Liver and Portosystemic Circulation Disorders: A Systematic Review

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim Children with chronic liver disease and portosystemic circulation disorders may have long‐term neurocognitive problems. Hypermanganesemia, reported in this group, could be a contributor. This systematic review aimed to characterise liver and portosystemic circulation disorders associated with hypermanganesemia and reported neurocognitive ...
Helena J. Kim, Susan M. Siew, Ji Hyun Moon, Tracey A. Williams, S. Murthy Chennapragada, Gordon Thomas, Shekeeb S. Mohammad   +6 more
wiley   +1 more source

HTLV-1 and HIV-1 co-infection: A case report and review of the literature

IDCases, 2016
HTLV type 1 and 2 are both involved in actively spreading epidemics, affecting over 15 million people worldwide. HTLV-1 has been described as the more clinically significant one, being associated with diseases such as adult T-cell leukemia and tropical ...
Carmen Isache, Michael Sands, Nilmarie Guzman, Danisha Figueroa   +3 more
doaj   +1 more source

Expanding the Phenotype of PARK‐PRKN to Spastic Paraplegia: A Report of Two Cases

Movement Disorders Clinical Practice, EarlyView.
Nicolas Geoffre, Thomas Ollivier, Guillaume Baille, Luc Defebvre, Vincent Huin, Eugenie Mutez   +5 more
wiley   +1 more source