Results 51 to 60 of about 10,460 (201)

Friedreich's ataxia presenting as adult-onset spastic paraparesis

, 1998
We have studied a man with an atypical form of Friedreich's ataxia (FRDA), who presented at age 26 years with a 2-year history of unsteadiness and clumsiness.
Gates, Peter C., Paris, Damien, McKinlay Gardner, R.J., Williamson, Robert, Forrest, Susan M.   +4 more
core   +1 more source

Hyperhomocysteinemia due to MTHFR deficiency - A treatable metabolic causes of progressive spastic paraparesis not to be missed

Annals of Movement Disorders
Methylenetetrahydrofolate reductase (MTHFR) deficiency is a rare autosomal-recessive disorder of folate metabolism, presenting with neurological symptoms such as spastic paraparesis, cognitive impairment, and psychosis.
Kamalesh Tayade, Jivan Morey, Haresh Bharote, Dnyaneshwar Asole, Anil Venkitachalam   +4 more
doaj   +1 more source

Evaluating the efficacy of obturator cryoneurolysis for hip adductor spasticity: An observational, prospective study

PM&R, EarlyView.
Abstract Background Hip adductor spasticity is a common affliction among patients with disorders of the central nervous system. Cryoneurolysis is a novel intervention for spasticity involving the application of extreme cold to a nerve. This induces axonal breakdown, relieving spasticity.
Fraser MacRae, Mahdis Hashemi, Paul Winston   +2 more
wiley   +1 more source

Association of late onset spastic paraparesis and dementia: Probably an autosomal dominant form of complicated paraplegia

, 1997
The hereditary paraplegias are a heterogeneous group of genetic disorders characterized mainly by spastic paraparesis, which may be found as an isolated 'pure form' known as Strumpell-Lorrain syndrome, or associated with a wide group of other ...
Bernal-Beltran, M.D.P., García-Cruz, D., Hernandez, A., Lizcano-Gil, L.A.   +3 more
core   +1 more source

Hepatic myelopathy as a rare but reversible neurological complication post transjugular intrahepatic portosystemic shunt (TIPS) insertion in liver cirrhosis

European Journal of Case Reports in Internal Medicine
Hepatic myelopathy is a rare but underrecognized complication of chronic liver disease characterized by pure motor, symmetric and spastic paraparesis without sphincter involvement.
Angela Zhu, Warren Clements, Robb Wesselingh, Natasha Janko   +3 more
doaj   +1 more source

Innovative technologies for gait rehabilitation in incomplete spinal cord injury: A systematic review and meta‐analysis

PM&R, EarlyView.
Abstract Objective This systematic review and meta‐analysis aimed to synthesize the current evidence on the efficacy of various technological interventions for gait rehabilitation in adults with incomplete spinal cord injury (iSCI). Literature survey MEDLINE (accessed by PubMed), Embase, Cochrane Central Register of Controlled Trials (Cochrane CENTRAL),
Emerson de Carvalho, Thainara Cruz da Rosa, Maira Jaqueline da Cunha, Aline S. Pagnussat   +3 more
wiley   +1 more source

Dorsolateral Cervical Cord T2 Hyperintensity in KIF1C‐Related Disease (Spastic Paraplegia 58): Two Long‐Duration Cases

Annals of Clinical and Translational Neurology
Pathogenic variants in KIF1C cause Spastic Paraplegia 58 (SPG58), typically presenting with cerebellar ataxia and spastic paraparesis. We report two unrelated patients with spastic paraparesis, cerebellar ataxia, and tremor. Whole‐exome sequence analysis
Akihiko Mitsutake, Masao Osaki, Takashi Matsukawa, Miho Osako, Chisen Takeuchi, Hiroyuki Ishiura, Jun Mitsui, Ryo Kurokawa, Harushi Mori, Yuji Takahashi, Jun Goto, Shoji Tsuji, Tatsushi Toda   +12 more
doaj   +1 more source

Input Visualizations to Track Health Data by Older Adults with Multiple Chronic Conditions

Computer Graphics Forum, EarlyView.
Abstract Older adults living with multiple chronic conditions (MCC) can considerably benefit from collecting and reflecting on their health data. Many older adults collect their health data using various approaches, such as digital tools or handwritten notebooks.
Shri Harini Ramesh, Foroozan Daneshzand, Matteo Sotelo, Mahsa Sinaei, Fateme Rajabiyazdi   +4 more
wiley   +1 more source

HTLV-1 and HIV-1 co-infection: A case report and review of the literature

IDCases, 2016
HTLV type 1 and 2 are both involved in actively spreading epidemics, affecting over 15 million people worldwide. HTLV-1 has been described as the more clinically significant one, being associated with diseases such as adult T-cell leukemia and tropical ...
Carmen Isache, Michael Sands, Nilmarie Guzman, Danisha Figueroa   +3 more
doaj   +1 more source

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source