Results 61 to 70 of about 29,371 (197)

HTLV screening and confirmatory testing among blood donors in São Paulo: A cross‐sectional study

Transfusion Medicine, EarlyView.
Abstract Introduction Human T‐cell lymphotropic virus types 1 and 2 (HTLV‐1/2) are transfusion‐transmissible retroviruses associated with severe diseases, and blood donor screening is mandatory in Brazil. Increasing HTLV‐related discard rates at our institution prompted this study to determine the prevalence and incidence of HTLV‐1/2 and to investigate
Suzete C. Ferreira, Anna S. Nishyia, Jerenice E. Ferreira, Claudia Di Lorenzo Oliveira, Cesar de Almeida‐Neto, Tila Fanciani, Katia C. Dantas, Juliana Derriga, Silvia Petrossi Gallo Polato, Nanci Salles, Vanderson Rocha, Alfredo Mendrone‐Junior   +11 more
wiley   +1 more source

Tau Accumulation in Primary Motor Cortex of Variant Alzheimer's Disease with Spastic Paraparesis

, 2017
We studied topographic distribution of tau and amyloid-β in a patient with variant Alzheimer's disease with spastic paraparesis (VarAD) by comparing AD patients.
최재용, 유영훈, 조한나, 이명식, 류철형   +4 more
core   +1 more source

A Rare Case of Fatty Acid Hydroxylase‐Associated Neurodegeneration in a Pakistani Boy With a Homozygous FA2H Variant

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Fatty acid hydroxylase‐associated neurodegeneration (FAHN) is an ultra‐rare neurological disorder caused by a mutation in the FA2H gene. Defective production of this gene leads to abnormal myelin formation, which subsequently causes neurodegeneration and brain iron accumulation.
Araj Naveed Siddiqui, Yamna Naveed Siddiqui, Noor ul Huda Abbasi, Raman Kumar, Hermann Yokolo   +4 more
wiley   +1 more source

A Family with Hereditary Spastic Paraparesis and Epilepsy [PDF]

Epilepsia, 1997
Summary: Purpose: We describe a family with hereditary spastic paraparesis (HSP) in which 4 of 6 affected members also have epilepsy.Methods: All family members were examined by 2 neurologists. Four affected and 3 unaffected family members had EEG recordings. Four affected members were investigated for other causes of spastic paraparesis and epilepsy.
S, Webb, N, Flanagan, N, Callaghan, M, Hutchinson   +3 more
openaire   +2 more sources

Efgartigimod Combined With Steroid Treatment for HAM/TSP: A Case Report

Annals of Clinical and Translational Neurology
HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive neurological disorder with limited treatment options. We report a 54‐year‐old female with decade‐long, progressive HAM/TSP, previously refractory to rituximab, who ...
Jiahui Zeng, Wotu Tian, Jingran Yang, Yanping Yang, Li Cao, Xinghua Luan   +5 more
doaj   +1 more source

Monoallelic POLR3A Variants Cause Early‐Onset Peripheral Neuropathy

Annals of Neurology, Volume 100, Issue 3, Page 655-671, September 2026.
Objective Biallelic variants in genes encoding the RNA polymerase III complex (Pol III) cause a spectrum of neurological disorders primarily affecting the central nervous system. Monoallelic variants have been reported in the POLR3B subunit only, associated with neurodevelopmental disorder, epilepsy, and peripheral neuropathy.
Luiza L. P. Ramos, Jevin M. Parmar, Robin Wijngaard, Bianca R. Grosz, Tamas Lazar, Ligia Mateiu, Steve Vucic, Kishore R. Kumar, Dennis Yeow, Laura I. Rudaks, Lonneke de Boer, Annemarie de Vreugd, David A. Koolen, Thatjana Gardeitchik, Anita Cairns, Krishnan Iyengar, Fernando Kok, Fernanda Barbosa Figueiredo, Alzira Alves de Siqueira Carvalho, Luiz S. Mageste Barbosa, Rodrigo Rezende Arantes, Tyler Rehbein, Jordan E. Bontrager, Elizabeth P. Wood, Janet E. Sowden, Gavin Monahan, Meutia Kumaheri, Ivy Cuijt, Melina Ellis, Gonzalo Perez‐Siles, Elyshia McNamara, Ronald van Beek, Celine B. Meijers, Ivaylo Tournev, Stephan Zuchner, Shoshana J. Wodak, Clara D. M. van Karnebeek, Nigel Laing, Liana N. Semcesen, David A. Stroud, David N. Herrmann, Velina Guergueltcheva, Marina L. Kennerson, Machteld M. Oud, Gianina Ravenscroft, Ayse Candayan, Albena Jordanova   +46 more
wiley   +1 more source

M233V PSEN1 mutation presenting as very early-onset dementia and spastic paraparesis

, 2014
M233V PSEN1 mutation found in a young female with AD and spastic ...
CERONI, MAURO, COSTA, ALFREDO, Bianchi, M., Vitali, P., Sinforiani, E, Vitali, P, RICCA, IVANA, Cereda, C, Bianchi, M, Cereda, C., Ricca, I, Gagliardi, S, Bini, P., Bini, P, Gagliardi, S.   +14 more
core  

Longitudinal Clinical Progression in X‐Linked Adrenoleukodystrophy: The AMNL Scoring System

Annals of the Child Neurology Society, Volume 4, Issue 3, Page 219-226, September 2026.
ABSTRACT Objective The current clinical nomenclature for individuals with ABCD1 gene dysfunction is often uninformative. The disorder was initially described as a combination of adrenal insufficiency and leukodystrophy, leading to the widespread use of “X‐linked adrenoleukodystrophy” (ALD).
Eda G. Kabak, Cecilie Videbaek, Marije M. C. Voermans, Björn M. van Geel, Keith van Haren, Stephan Kemp, Diederik van de Beek, Marc Engelen   +7 more
wiley   +1 more source

Human T-lymphotropic virus type 1 (HTLV-1) infection and spastic paraparesis. Advances and diagnosis 35 years after its discovery

Iatreia, 2017
Human T-lymphotropic virus type 1 (HTLV-1) causes disorders such as chronic inflammatory progressive myelopathy, which is known as HTLV-1associated myelopathy (MAH), characterized by spastic paraparesis symptoms.
Rivera-Caldón, Cristhian Camilo, López-Valencia, David, Zamora-Bastidas, Tomás Omar, Dueñas-Cuéllar, Rosa Amalia, Mora-Obando, Diana Lorena   +4 more
doaj   +1 more source

A Comparative Study on β‐ODAP Level, Polyphenolic Content and Antioxidant Activity Across Three Lathyrus sativus L. Cultivars

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
β‐ODAP content in three diverse Lathyrus sativus L. cultivars. ABSTRACT Grass pea (Lathyrus sativus L.) is an old crop highly resistant to climate changes and drought. Despite its nutritional benefits, it represents a source of β‐ODAP, a non‐protein amino acid which causes neurolathyrism.
Giulia Gentile, Lorenza Marinaccio, Eleonora Procino, Angelo Cichelli, Adriano Mollica, Azzurra Stefanucci   +5 more
wiley   +1 more source