Results 81 to 90 of about 29,371 (197)

HTLV-I negative tropical spastic paraparesis: a scientific challenge Paraparesia espástica tropical HTLV-I negativa: um desafio científico

Arquivos de Neuro-Psiquiatria, 2001
We reviewed the historical, clinical and etiological aspects of the progressive chronic spastic myelopathies of unknown etiology, disserting on the clinical similarities between HTLV-I seropositive and seronegative tropical spastic paraparesis (TSP), as ...
Carlos Mauricio De Castro-Costa, Herwig Carton, Terezinha J. T. Santos   +2 more
doaj   +1 more source

KIF1C mutations in two families with hereditary spastic paraparesis and cerebellar dysfunction

, 2014
International audienceBackground Hereditary spastic paraparesis (HSP) (syn. Hereditary spastic paraplegia, SPG) are a group of genetic disorders characterised by spasticity of the lower limbs due to pyramidal tract dysfunction.
Dor, Talya, Bouhouche, Ahmed, Brice, Alexis, Cinnamon, Yuval, Schuelke, Markus, Benomar, Ali, Bouslam, Naima, Meyer, Vincent, Durr, Alexandra, Stevanin, Giovanni, Raymond, Laure, Shaag, Avraham, Gaussen, Marion, Edvardson, Simon   +13 more
core   +1 more source

Tropical spastic paraparesis in Kerala, South India

, 2003
Tropical Spastic Paraparesis (TSP) is an uncommon myeloneuropathy with an insular geographic distribution. In 1985, Human T-lymphotropic virus type I (HTLV-1) was reported to be a possible etiological factor.1 We did an epidemiological, clinical and ...
A. Oomman, M. Madhusoodanan
core   +4 more sources

Tropical spastic paraparesis.

Folia neuropathologica, 2002
Human T-cell lymphotropic virus type I (HTLV-I) is the cause of endemic tropical spastic paraparesis (TSP) or HTLV-I-associated myelopathy (HAM). Because TSP/HAM is not a fatal disease, the neuropathology of this disease, albeit relatively well understood, is based on the examination of just a few incidental cases.
J, Buczyński, R, Yanagihara, C, Mora, L, Cartier, A, Verdugo, F, Araya, L, Castillo, C J, Gibbs, C D, Gajdusek, P, Rogers-Johnson, P P, Liberski   +10 more
openaire   +1 more source

An efficient multidisciplinary approach in a pregnant patient with hereditary spastic paraparesis treated by intrathecal baclofen therapy: A case report

, 2021
Literature regarding cases of pregnant patients with hereditary spastic paraparesis (Strumpell-Lorrain disease) and those treated by intrathecal baclofen therapy is sparse.
Gustin, Thierry, Dereine, T, Deltombe, Thierry, Roland, V, Fostier, Michèle   +4 more
core  

ALDH18A1‐related hereditary spastic paraplegia and developmental and epileptic encephalopathy with spike‐wave activation in sleep: Expanding the clinical phenotype

Annals of the Child Neurology Society
Objective We present the cases of two sisters, both harboring the same ALDH18A1 gene mutations, who presented with a complex clinical phenotype characterized by spastic paraparesis with ataxia, epileptic encephalopathy, severe psychomotor deficits, and ...
Giusi Ferrara, Gianni Cutillo, Irene Peterlongo, Eleonora Minacapilli, Maria Iascone, Pierangelo Veggiotti, Isabella Fiocchi   +6 more
doaj   +1 more source

Overlapping Aicardi–Goutières and Singleton–Merten syndromes with a heterozygous gain-of-function mutation in IFIH1 mimicking juvenile idiopathic arthritis

Immunological Medicine
Aicardi–Goutières syndrome (AGS) and Singleton–Merten syndrome (SMS) are associated with heterozygous gain-of-function mutations in the interferon induced with helicase C domain 1 (IFIH1) gene.
Susumu Yamazaki, Shuya Kaneko, Asami Shimbo, Hitoshi Irabu, Ryo Ogino, Takayuki Miyamoto, Kazushi Izawa, Yuko Segawa, Jun Kakizaki, Masaaki Mori, Masaki Shimizu   +10 more
doaj   +1 more source

Spastic paraparesis: putative toxicants, determinants and contributing factors in public health [PDF]

, 2016
Cassava is a staple food in many tropical countries, most notably Africa. Consumption of cassava, especially the bitter cassava varieties, can lead to a neurological disorder called “spastic paraparesis” or “konzo” in West Africa; most often epidemic ...
Praekunatham, Hirunwut
core  

X-linked adrenoleukodystrophy as an etiological cause of progressive spastic paraplegia: A case report

Journal of International Medical Research
X-linked adrenoleukodystrophy is a rare peroxisomal disorder caused by mutations in ABCD1 , thereby resulting in impaired β-oxidation of very long-chain fatty acids.
Min Cheol Chang, Seoyon Yang
doaj   +1 more source

Mania associated with complicated hereditary spastic paraparesis

, 2011
Hereditary spastic paraparesis (HSP) is an inherited group of neurological disorders with progressive lower limb spasticity. HSP can be clinically grouped into pure and complicated forms.
Raghavendra B Nayak, Nanasaheb M Patil, Aditya A Pandurangi, Govind S Bhogale   +3 more
core   +1 more source