Results 31 to 40 of about 70,828 (231)

Clinical, biochemical, radiological, and genetic profile of patients with homocysteine remethylation pathway defect and spastic paraplegia

Annals of Indian Academy of Neurology, 2021
Objectives: The objective of this study is to describe the clinical, biochemical, radiological, and genetic profile of patients presenting with progressive spastic paraparesis due to homocysteine remethylation pathway defect.
Hansashree Padmanabha, Rohan Mahale, Rita Christopher, Gautham Arunachal, Maya Bhat, Mahammad Samim Mondal, Ram Murthy Anjanappa, Ravindranadh Chowdhary Mundlamuri, Ravi Yadav, Seena Vengalil, Pooja Mailankody, Pavagada S Mathuranath, Sadanandavalli R Chandra, Atchayaram Nalini   +13 more
doaj   +1 more source

Human T-lymphotropic virus type 1 (HTLV-1) and cellular immune response in HTLV-1-associated myelopathy/tropical spastic paraparesis

Journal of Neurovirology, 2020
Human T-lymphotropic virus type 1 (HTLV-1) is associated with adult T cell leukemia/lymphoma and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Satoshi Nozuma, R. Kubota, S. Jacobson
semanticscholar   +1 more source

Monogenic lupus due to spondyloenchondrodysplasia with spastic paraparesis and intracranial calcification: case-based review

Rheumatology International, 2020
Spondyloenchondrodysplasia (SPENCD) is a rare skeletal dysplasia characterized with platyspondyly and metaphyseal lesions of the long bones mimicking enchondromatosis, resulting in short stature. SPENCD often coexists with neurologic disorders and immune
B. Kara, Z. Ekinci, S. Şahin, Mesut Gungor, A. S. Gunes, K. Ozturk, A. Adroviç, A. Çefle, M. Inanç, A. Gul, O. Kasapcopur   +10 more
semanticscholar   +1 more source

The Barriers of Coping with HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis: A Content Analysis Study [PDF]

Journal of Evidence-Based Care, 2023
Background: HTLV-1-associated myelopathy is associated with constant stress, so it is very important to cope with this disease. To improve the coping of patients with this disease, it is necessary to deeply identify its barriers.Aim: The present study ...
Malihe Davoudi, Reza Boostani, Zahra Sadat Manzari   +2 more
doaj   +1 more source

A rare complication of cirrhosis: Hepatic myelopathy

Journal of Spinal Surgery, 2014
Introduction: Hepatic myelopathy is characterized by spastic paraparesis and minimal sensory abnormalities in patients with cirrhosis, particularly those with portosystemic shunts that have been created surgically or have occurred spontaneously ...
Sofiene Bouali, Adenane Boubaker, Asma Bouhoula, Jalel Kallel, Aoiuj Lassaad, Hafedh Jemel   +5 more
doaj   +1 more source

Novel OPA1 mutation featuring spastic paraparesis and intestinal dysmotility

Molecular Genetics and Metabolism Reports, 2014
A 58-year-old man with optic atrophy, spastic paraparesis, axonal sensorimotor peripheral neuropathy and intestinal dysmotility harbors a novel heterozygous missense mutation in the mitochondrial import signal peptide of OPA1.
Mohamed Kazamel, Lee-Jun Wong, Margherita Milone   +2 more
doaj   +1 more source

From cirrhosis to paraparesis [PDF]

Romanian Journal of Neurology, 2019
We present the case of a 61-years-old male, diagnosed with liver cirrhosis, portal hypertension and type II diabetes mellitus, who developed bilateral signs of Parkinsonism, intention tremor and spastic paraparesis.
Ioan-Cristian Lupescu, Speranta Iacob, Ioana Gabriela Lupescu, Liliana Gheorghe, Adriana Octaviana Dulamea   +4 more
doaj   +1 more source

Immunovirological markers in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Retrovirology, 2019
Human T cell lymphotropic virus 1 (HTLV-1) is a human retrovirus and infects approximately 10–20 million people worldwide. While the majority of infected people are asymptomatic carriers of HTLV-1, only 4% of infected people develop HTLV-1-associated ...
Yoshimi Enose-Akahata, S. Jacobson
semanticscholar   +1 more source

Real-world clinical course of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in Japan

Orphanet Journal of Rare Diseases, 2019
BackgroundAs human T-cell leukemia virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a rare chronic neurological disease, large scale studies to collect continuous clinical data have been difficult to conduct ...
S. Tsutsumi, Tomoo Sato, N. Yagishita, J. Yamauchi, N. Araya, D. Hasegawa, M. Nagasaka, A. Coler-Reilly, E. Inoue, A. Takata, Y. Yamano   +10 more
semanticscholar   +1 more source

Proposal of Classification Criteria for HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis Disease Activity

Frontiers in Microbiology, 2018
Human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a rare chronic neuroinflammatory disease. While the disease usually progresses slowly without remission, there is a subgroup of patients with rapid
Tomoo Sato, N. Yagishita, K. Tamaki, E. Inoue, D. Hasegawa, M. Nagasaka, Hiroko Suzuki, N. Araya, A. Coler-Reilly, Y. Hasegawa, Y. Tsuboi, A. Takata, Y. Yamano   +12 more
semanticscholar   +1 more source