Results 101 to 110 of about 164,048 (382)

Design of a Multi-Sensor System for Exploring the Relation between Finger Spasticity and Voluntary Movement in Patients with Stroke [PDF]

open access: gold, 2022
Bor-Shing Lin   +8 more
openalex   +1 more source

REEP1 Accumulation Disrupts ER Integrity and Drives Spinal Motoneuron Degeneration in Distal Hereditary Motor Neuropathy

open access: yesAdvanced Science, EarlyView.
REEP1 contributes to endoplasmic reticulum (ER) shaping. Variants either cause cortical motoneuron degeneration and hereditary spastic paraplegia (HSP) or spinal motoneuron degeneration and distal hereditary motor neuropathy (dHMN). Knockout causes less complex ER structures and cortical motoneuron loss.
Andrea Bock   +25 more
wiley   +1 more source

The Adverse Effect of Spasticity on 3-Month Poststroke Outcome Using a Population-Based Model

open access: yesStroke Research and Treatment, 2014
Several devices and medications have been used to address poststroke spasticity. Yet, spasticity’s impact on outcomes remains controversial. Using data from a cohort of 460 ischemic stroke patients, we previously published a validated multivariable ...
S. R. Belagaje   +11 more
doaj   +1 more source

Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment

open access: yesAdvanced Science, EarlyView.
Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr.   +20 more
wiley   +1 more source

Assessment of Health Care Costs and Total Baclofen Use Associated With Targeted Drug Delivery for Spasticity [PDF]

open access: green, 2023
Vishal Venkatraman   +6 more
openalex   +1 more source

A Wearable System Featuring Biomimetic Spatially Distributed Iontronic Sensing Array for Dynamic Monitoring of Deep Tissue Modulus

open access: yesAdvanced Science, EarlyView.
A fully wearable system enables real‐time, dynamic, and accurate monitoring of Young's modulus in multilayer tissues containing deep muscle. It demonstrates high accuracy and robustness across simulations, benchtop validations, and human testing. It quantifies edema severity and tracks muscle stiffness during rest, loaded elbow flexion, rope skipping ...
Zhenning Wang   +12 more
wiley   +1 more source

Current clinical practice of Irish physiotherapists and occupational therapists in the assessment and treatment of spasticity in adults [PDF]

open access: yesIrish Journal of Occupational Therapy
Purpose – This paper aims to understand the clinical practice of physiotherapists and occupational therapists in the Republic of Ireland in the assessment and treatment of spasticity in adults, to inform and improve spasticity management practice.
Deirdre Manning   +2 more
doaj   +1 more source

A hopeful therapy for Niemann-Pick C diseases [PDF]

open access: yes, 2017
Not abstract ...
Erickson, Robert P.   +1 more
core   +1 more source

Management of spasticity [PDF]

open access: yesAge and Ageing, 1998
Spasticity is a major challenge to the rehabilitationteam. Spasticity can prevent or hamper function, causepain, disturb sleep, cause unnecessary complicationsand present major difficulties for care workers. Thisarticle reviews the variety of options available for theclinical management of spasticity.
openaire   +2 more sources

An ITPR1 Variant in the IP3‐ITPR1 Binding Pocket Associated With a Clinical Phenotype of Athetoid Cerebral Palsy

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT A de novo, missense variant in ITPR1‐inositol 1,4,5‐trisphosphate receptor type 1 (ITPR1), p.(Tyr567Cys), was identified by trio whole‐genome sequencing in an individual diagnosed with Spinocerebellar ataxia 29 (SCA29) who was affected by cerebral palsy and global developmental delay.
Thania Ordaz   +12 more
wiley   +1 more source

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