Results 71 to 80 of about 4,914,372 (218)

A Randomized, Double-Blind, Active Control, Multicenter, Phase 3 Study to Evaluate the Efficacy and Safety of Liztox® versus Botox® in Post-Stroke Upper Limb Spasticity

open access: yesToxins, 2023
Botulinum toxin type A (BTX-A) injection is a commonly used therapeutic intervention for upper limb spasticity in stroke patients. This study was designed as a randomized, active-drug-controlled, double-blind, multicenter, phase 3 clinical trial to ...
Dong Hyun Ye   +6 more
doaj   +1 more source

Spasticity: A review of Methods for Assessment and Treatment

open access: yesIranian Rehabilitation Journal, 2011
Spasticity is the condition resulting of corticispinal damage as occurs in some neurological diseases. The aim of the article is to review the literature on assessment and treatment of spasticity and spastic limbs.
Mohammad Amouzadeh Khalili   +1 more
doaj  

New insights into the pathophysiology of post-stroke spasticity

open access: yesFrontiers in Human Neuroscience, 2015
Spasticity is one of many consequences after stroke. It is characterized by a velocity-dependent increase in resistance during passive stretch, resulting from hyperexcitability of the stretch reflex. The underlying mechanism of the hyperexcitable stretch
Sheng eLi, Gerard eFrancisco
doaj   +1 more source

Effects of Diagnostic Tibial Nerve Block and Selective Tibial Nerve Neurotomy on Spasticity and Spastic co-contractions: A Retrospective Observational Study

open access: yesJournal of Rehabilitation Medicine, 2023
Objective: To assess the effects of diagnostic nerve block and selective tibial neurotomy on spasticity and co-contractions in patients with spastic equinovarus foot. Methods: Among 317 patients who underwent a tibial neurotomy between 1997 and 2019, 46
Jean-Philippe Lamora   +2 more
doaj   +1 more source

Pre- and Post-alpha Motoneuronal Control of the Soleus H-reflex during Sinusoidal Hip Movements in Human Spinal Cord Injury [PDF]

open access: yes, 2006
The aim of this study was to establish the contribution of hip-mediated sensory feedback to spinal interneuronal circuits during dynamic conditions in people with incomplete spinal cord injury (SCI).
Chaudhuri, Debjani   +3 more
core   +2 more sources

Shared and distinct voxel-based lesion-symptom mappings for spasticity and impaired movement in the hemiparetic upper limb

open access: yesScientific Reports, 2022
Hemiparesis and spasticity are common co-occurring manifestations of hemispheric stroke. The relationship between impaired precision and force in voluntary movement (hemiparesis) and the increment in muscle tone that stems from dysregulated activity of ...
Silvi Frenkel-Toledo   +7 more
doaj   +1 more source

Role of peripheral quantitative computed tomography in identifying disuse osteoporosis in paraplegia [PDF]

open access: yes, 2009
Objective: Disuse osteoporosis is a major long-term health consequence of spinal cord injury (SCI) that still needs to be addressed. Its management in SCI should begin with accurate diagnosis, followed by targeted treatments in the most vulnerable ...
A Frotzler   +22 more
core   +1 more source

Assessment of cyclobenzaprine in the treatment of spasticity [PDF]

open access: yesJournal of Neurology, Neurosurgery & Psychiatry, 1972
The efficacy of cyclobenzaprine 60 mg/day in the treatment of spasticity was assessed in a double-blind crossover trial of two weeks' duration in 15 patients suffering from cerebral or spinal spasticity. Independent clinical and electromyographic methods were used. The effects of cyclobenzaprine did not differ significantly from those of placebo.
P, Ashby, D, Burke, S, Rao, R F, Jones
openaire   +2 more sources

Whole plant cannabis extracts in the treatment of spasticity in multiple sclerosis: a systematic review

open access: yesBMC Neurology, 2009
Background Cannabis therapy has been considered an effective treatment for spasticity, although clinical reports of symptom reduction in multiple sclerosis (MS) describe mixed outcomes.
Rowland Marie, Lakhan Shaheen E
doaj   +1 more source

Integrated Management of Multiple Sclerosis Spasticity and Associated Symptoms Using the Spasticity-Plus Syndrome Concept: Results of a Structured Specialists' Discussion Using the Workmat® Methodology

open access: yesFrontiers in Neurology, 2021
Background: Multiple sclerosis (MS) treatment has radically improved over the last years; however, MS symptom management is still challenging. The novel Spasticity-Plus syndrome was conceptualized to frame several spasticity-related symptoms that can be ...
Oscar Fernandez   +7 more
doaj   +1 more source

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