Results 81 to 90 of about 5,199,774 (263)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Spatial wave assimilation by integration of artificial neural network and numerical wave model

open access: yes, 2022
Ocean wave information is generally limited, particularly at nearshore, and attempts have been made to reconstruct spatial wave information, such as by using numerical wave models.
Oo, Ye Htet, Zhang, Hong
core   +1 more source

Dissociated Spatial-Arithmetic Associations in Horizontal and Vertical Dimensions

open access: yesFrontiers in Psychology, 2017
Spatial–numerical associations (small numbers—left/lower space and large numbers—right/upper space) are regularly found in elementary number processing.
Dixiu Liu   +12 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Investigating spatial-numerical associations in both directions with manual responses

open access: yes, 2021
The spatial-numerical association of response codes (SNARC) effect is one of the most prominent and well-studied phenomena of the last three decades. It refers to the finding that left-hand responses are faster (and more accurate) to small as compared to
Peter Wühr, Melanie Richter
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Numerical Simulation of a Turbulent Flow in a Channel with Surface Mounted Cubes [PDF]

open access: yes, 1998
In this paper we report on a fourth-order, spectro-consistent simulation of a complex turbulent flow. A spatial discretization of a convection-diffusion equation is termed spectro-consistent if the spectral properties of the convective and diffusive ...
Veldman, A.E.P.   +5 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

No spatial-numerical mapping in cultures with mixed-reading habits

open access: yesFrontiers in Human Neuroscience, 2014
Reading habits are thought to play an important role in the emergence of cultural differences in visuo-spatial and numerical tasks. Left-to-right readers show a slight visuo-spatial bias to the left side of space and automatically associate small numbers
Neda eRashidi-Ranjbar   +6 more
doaj   +1 more source

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