Results 101 to 110 of about 6,899,247 (329)

Extracting Spatial Information from Noise Measurements of Multi-Spatial-Mode Quantum States

, 2012
We show that it is possible to use the spatial quantum correlations present in twin beams to extract information about the shape of a mask in the path of one of the beams.
A. Gatti, A. Gatti, A. M. Marino, A.F. Abouraddy, B.I. Erkmen, C.F. McCormick, C.W. Helstrom, D.V. Strekalov, E. Brambilla, E. Brambilla, H. Bechmann-Pasquinucci, J. B. Clark, J.B. Clark, L.A. Lugiato, L.A. Lugiato, L.M. Duan, M. Lassen, M. Martinelli, M.I. Kolobov, M.I. Kolobov, N. Treps, P. D. Lett, P. Navez, Q. Glorieux, R.S. Bennink, T.B. Pittman, V. Boyer, V. Boyer, V. Giovannetti   +28 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Towards general spatial intelligence [PDF]

, 2008
The goal of General Spatial Intelligence is to present a unified theory to support the various aspects of spatial experience, whether physical or cognitive.
Domingue, John, Tanasescu, Vlad
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Assessing intratumor heterogeneity and tracking longitudinal and spatial clonal evolutionary history by next-generation sequencing [PDF]

, 2016
Yuchao Jiang, Yu Qiu, Andy J. Minn, Nancy R. Zhang   +3 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Robust Creation of Entanglement between Ions in Spatially Separate Cavities [PDF]

, 2003
Dan E. Browne, Martin B. Plenio, Susana F. Huelga   +2 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Methodological approaches to exploring the spatial variation in social impacts of protected areas: An intercomparison of Bayesian regression modeling approaches and potential implications

Mathematical Biosciences and Engineering
Protected Areas (PAs) are widely used to conserve biodiversity by protecting and restoring ecosystems while also contributing to socio-economic priorities.
Chrysovalantis Malesios, Nikoleta Jones , Alfie Begley , James McGinlay   +3 more
doaj   +1 more source

Monte Carlo Simulations of Enzyme Reactions in Two Dimensions: Fractal Kinetics and Spatial Segregation [PDF]

, 2002
Hugues Berry
openalex   +1 more source