Results 91 to 100 of about 755,208 (308)
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Verbal Ability and Spatial Task [PDF]
, 1984 122 verbally and spatially able children aged 10 to 15 yr. performed the portable-rod-and-frame task to permit comparison of the procedures they used to do it. When spatial ability was higher than verbal scores, a spatial procedure was more likely used;
Bruce M. Shore, Shawn M. Carey
core +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
ISPRS International Journal of Geo-Information, 2018 In this article, we use eye-tracking methods to analyze the differences in spatial ability between geographers and non-geographers regarding topographic maps, as reflected in the following three aspects: map-based spatial localization, map-based spatial ...
Weihua Dong +3 more
doaj +1 more source
The comparative efficacy of 2D-versus 3D-based media design for influencing spatial visualization skills [PDF]
, 2014 [[abstract]]This study explored the effects of 2D- versus 3D-based media representations on the influence of the spatial visualization ability of undergraduate science majors.
Wang, H. C.;Chang, C. Y.;Li, T. Y.
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Forecasting Regional Labor Market Developments under Spatial Autocorrelation [PDF]
, 2007 Because of heterogeneity across regions, economic policy measures are increasingly targeted at the regional level and, therefore, require regional forecasts. The data available to compute regional forecasts are usually a pseudo panel of a limited number
Simonetta Longhi +5 more
core +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
The influence of spatial ability and experience on performance during spaceship rendezvous and docking [PDF]
, 2015 Manual rendezvous and docking (manual RVD) is a challenging space task for astronauts. Previous research showed a correlation between spatial ability and manual RVD skills among participants at early stages of training, but paid less attention to experts.
Zhang, Jingyu +5 more
core