Results 91 to 100 of about 6,272,149 (253)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Does spatial visualization ability improve after studying technical drawing? [PDF]

open access: yes, 2008
Spatial ability, Spatial visualization, Inductive reasoning, Technical drawing, Training, Rasch model,
Có, Patricia   +8 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Wayfinding in autism spectrum disorders [PDF]

open access: yes, 2011
This study featured the use of ... a comprehensive battery [of tests], designed to assess general spatial ability as well as varieties of spatial cognition (including spatial navigation)
Ing, Natalia, Natalia Ing
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

FUTURE OF SPATIAL ABILITY RESEARCHES AND EDUCATION: A REVIEW [PDF]

open access: yes, 2019
The present paper deals with the future trends of researches in the area of spatial ability and its implication on education. Researches on spatial ability are predicted to continue with two concurrent themes: its association with intelligence and the ...
Tanweer, Mohammad
core   +1 more source

No relationship between gender stereotypes and mental rotation in preschool girls

open access: yesFrontiers in Psychology
Gender stereotypes about spatial ability have been proposed as a contributing factor to the gender gap in STEM. This goal of this study was to investigate whether implicit gender stereotypes regarding spatial ability are associated with mental rotation ...
W. Miro Ebert   +2 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

INVESTIGATION OF THREE DIMENSIONAL SPATIAL ABILITY LEVELS [PDF]

open access: yes, 2019
Spatial ability is an important factor affecting student achievement in science and mathematics education. In this study, it is aimed to investigate the spatial ability levels of students studying in chemistry department.
Sivrikaya, Serpil Özkurt
core   +1 more source

Spatial and non-verbal reasoning abilities in first-year female DVM students before and after 4 h of canine osteology training or 19 h of canine dissection: preliminary study

open access: yesFrontiers in Veterinary Science
Spatial ability refers to human cognitive ability to form, retrieve, and mentally manipulate models of spatial nature. This critical component of human intellect is relevant on a wide spectrum of professional disciplines including engineering ...
J. Claudio Gutierrez   +3 more
doaj   +1 more source

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