Results 61 to 70 of about 6,272,149 (253)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Spatial ability, urban wayfinding and location-based services:a review and first results [PDF]

open access: yes, 2004
Location-Based Services (LBS) are a new industry at the core of which are GISand spatial databases. With increasing mobility of individuals, the anticipatedavailability of broadband communications for mobile devices and growingvolumes of location ...
Li, C
core  

Kesalahan Konsep Descriptive Geometry Mahasiswa terhadap Kemampuan Spasial dalam Pembelajaran Daring di Masa Pandemi COVID-19

open access: yesJurnal Elemen, 2021
Spatial ability is one of the essential abilities to be mastered by students, especially in geometry. There is not much research, especially in Indonesian, that examines students' spatial abilities and their relation to Descriptive Geometry.
Aris Hadiyan Wijaksana   +1 more
doaj  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

SPATIAL ABILITY AND SCIENCE EDUCATION: A REVIEW OF CORRELATIONAL STUDIES [PDF]

open access: yes, 2019
Out of the four approaches in researches on spatial thinking in undergraduate science curricula, viz. correlation studies, studies on training of spatial ability, focused studies and dynamic spatial representations studies; this paper reviews the ...
Tanweer, Mohammad
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Mental rotation abilities of gymnasts and soccer players: a comparison of egocentric and object-based transformations. An exploratory and preliminary study

open access: yesFrontiers in Psychology
Background and objectivesThe experience obtained from motor expertise may contribute to and enhance the development of particular visuo-spatial abilities.
Thomas Jürgen Klotzbier, Nadja Schott
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Visual-Spatial Ability: Important in STEM, Ignored in Gifted Education [PDF]

open access: yes, 2014
Visual–spatial ability is a multifaceted component of intelligence that has predictive validity for future achievement in science, technology, engineering, and mathematics (STEM) occupations.
Andersen, Lori
core   +1 more source

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